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Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

Massachusetts , United-states , Kateryna-kon , Image-credit , Massachusetts-general-hospital , Heart , Cute-respiratory-distress-syndrome , Lood , Lood-pressure , Ardiomyopathy , Ardiovascular-disease

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

United-kingdom , Science-advances , Image-credit , Coronavirus-disease-covid-19 , Ntibodies , Lood , D4 , Ell , Oronavirus , Ytokine , Ytometry

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

Cancer , Ancer-treatment , Atural-killer-cells , Ioengineering , Lood , One , One-marrow , Art-cell , Ell , Ytokine , Ytotoxicity

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

Milieu-int , Bacillus-calmette-gu , Immune-response , Moking , Ntigen , Lood , Ell , Oronavirus , Pg , Ytokine , Ytokines

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Study reveals that both lacto-ovo vegetarian and Mediterranean diets positively impact apolipoprotein levels and cardiovascular disease risk factors, with Mediterranean diet showing a more substantial effect on apolipoprotein levels, particularly in women and older individuals with fewer CVD risk factors.

Briana-jackson , European-society-of-cardiology , European-society , Cardiovascular-prevention , Heart , Eart-disease , Egetarian , Polipoprotein , Lood , Arbohydrate , Ardiology , Ardiovascular-disease

Black cumin: Ancient superseed with modern health benefits

Review discusses the multifaceted role of Nigella sativa in treating cardiometabolic diseases, highlighting its bioactive components like thymoquinone, which contribute to its antioxidant, anti-inflammatory, and anti-dyslipidemic properties.

China , Colombia , Greece , Malaysia , Brazil , Canada , Saudi-arabia , Iran , Egypt , Pakistan , India , Chinese

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

Kyoto , Japan , Jinan , Shandong , China , Weighted-gene-network-analysis , First-affiliated-hospital-of-jinan-university , Clinical-microbiology , First-affiliated-hospital , Jinan-university , Weighted-gene-co-expression-network-analysis

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Promising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe Covid-19.

New-york , United-states , Cambridge , Cambridgeshire , United-kingdom , Justin-stebbing , Santa-monica , Marc-van-dijk , Norton-cancer-center , Nature-communications , Providence-saint-john-health-center , Anglia-ruskin-university

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

Max-delbr , Christine-kocks , Klaus-rajewsky , Xun-li , Helmholtz-association , Cancer-lab , Molecular-medicine , Professor-klaus-rajewsky , Immune-regulation , Gene , Lood

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

The association between biomarkers of cholesterol homeostasis and mortality in critically ill patients.

Ottawa , Ontario , Canada , Surfsup-shutterstock , Ovid-medline , Health-literature , Cumulative-index , Allied-health-literature , Cochrane-central-register , Controlled-trials , Ottawa-scale , Cholesterol