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POSTECH: Alleviating Inflammation by NO-Scavenging and Delivering Drugs

Have you experienced fever or swelling in the morning with stiff or sore joints? The cause of rheumatoid arthritis – a chronic inflammatory joint disease that can occur in various joints such as hands, wrists, feet and ankles – is still unknown. As s ....

Jong Kim , Taejeong Kim , Department Of Chemistry , Creative Consilience Program , Omniamed Co Ltd , Research Program Of The National Foundation , Ministry Of Science , Creative Materials Discovery Program , Won Jong Kim , Advanced Materials , Professor Won Jong Kim , Consilience Program , Basic Research Program , National Research Foundation , ஜாங் கிம் , துறை ஆஃப் வேதியியல் , அமைச்சகம் ஆஃப் அறிவியல் , படைப்பு பொருட்கள் கண்டுபிடிப்பு ப்ரோக்ர்யாம் , வென்றது ஜாங் கிம் , ப்ரொஃபெஸர் வென்றது ஜாங் கிம் , அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , தேசிய ஆராய்ச்சி அடித்தளம் ,

A tripartite-chromosome E. coli strain allows the chromosome isolation and implantation

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IMAGE: The E. coli chromosome was split into three 1-Mb chromosomes, and the chromosome was used for genome implantation.
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Credit: Rikkyo University
Escherichia coli (
E. coli) genome, consisting of 4.6 million base pairs of a single circular DNA, is too large to manipulate following the extraction and transfer to other bacteria.
In the present study, a group of Rikkyo University researchers led by Assistant Professor Takahito Mukai and Professor Masayuki Su etsugu has succeeded in splitting the E.coli genome into tripartite-genome of 1 million base pairs per genome (split-genome) using the smallest
E. coli genome strain established so far. In addition, they successfully extracted the split-genome from bacteria and installed it in other ....

Takahito Mukai , Masayuki Suetsugu , Nucleic Acids Research On , Rikkyo University , Strategic Basic Research Program , Core Research For Evolutional Science , Assistant Professor Takahito Mukai , Professor Masayuki Su Etsugu , Nucleic Acids Research , Basic Research Program , Core Research , Evolutional Science , Molecular Biology , றிக்கியோ பல்கலைக்கழகம் , மூலோபாய அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , அடிப்படை ஆராய்ச்சி ப்ரோக்ர்யாம் , கோர் ஆராய்ச்சி ,

Researchers generate human-monkey chimeric embryos

Credit: Weizhi Ji, Kunming University of Science and Technology
Investigators in China and the United States have injected human stem cells into primate embryos and were able to grow chimeric embryos for a significant period of time up to 20 days. The research, despite its ethical concerns, has the potential to provide new insights into developmental biology and evolution. It also has implications for developing new models of human biology and disease. The work appears April 15 in the journal
Cell.
As we are unable to conduct certain types of experiments in humans, it is essential that we have better models to more accurately study and understand human biology and disease, says senior author Juan Carlos Izpisua Belmonte, a professor in the Gene Expression Laboratory at the Salk Institute for Biological Sciences. An important goal of experimental biology is the development of model systems that allow for the study of human diseases under in vivo conditions. ....

United States , Izpisua Belmonte , Weizhi Ji , Juan Carlos Izpisua Belmonte , National Natural Science Foundation Of China , University Of Science , Moxie Foundation , Major Basic Research Project Of Science , Gene Expression Laboratory , Technology Of Yunnan , Salk Institute For Biological Sciences , Development Program , National Key Research , Yunnan Fundamental Research , Technology In Yunnan , Salk Institute , Kunming University , National Natural Science Foundation , Major Basic Research Project , Key Projects , Basic Research Program , Yunnan Province , High Level Talent Cultivation Support Plan , Yunnan Fundamental Research Projects , Cell Press , Cell Biology ,

Respiratory viral pathogens, quickly caught on-site!

Respiratory viral pathogens, quickly caught on-site!
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South Korea , Nano Plasmonic , Young Lee , Samsung Medical Center , Ayoung Woo Of Samsung Medical Center , Ministry Of Food , Korea Institute Of Materials Science , Ministry Of Science , Vitro Diagnostic Research Center , Sung Gyu Park , Korea Institute , Materials Science , President Jung Hwan Lee , Min Young Lee , Ayoung Woo , Samsung Medical , Polymerase Chain Reaction , Fundamental Research Program , தெற்கு கொரியா , இளம் லீ , சாம்சங் மருத்துவ மையம் , அமைச்சகம் ஆஃப் உணவு , கொரியா நிறுவனம் ஆஃப் பொருட்கள் அறிவியல் , அமைச்சகம் ஆஃப் அறிவியல் , கொரியா நிறுவனம் , பொருட்கள் அறிவியல் ,

HKUMed discovers a novel mediator of liver fibrosis and its underlying mechanism that can be a new therapeutic target

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HKUMed discovers a novel mediator of liver fibrosis and its underlying mechanism that can be a new therapeutic target
HKUMed discovers a novel mediator of liver fibrosis and its underlying mechanism that can be a new therapeutic target. The research was led by Dr Ruby Hoo Lai-chong (second from left), Assistant Professor, Department of Pharmacology and Pharmacy, HKUMed and Co-investigator of State Key Laboratory of Pharmaceutical Biotechnology, HKU. Dr Wu Xiaoping (second from right), post-doctoral fellow, Department of Pharmacology and Pharmacy, HKUMed is the first author. Other research team members include: Ms Zong Jiuyu (left) and Ms Zhang Zixuan (right), postgraduate student, Department of Pharmacology and Pharmacy, HKUMed. ....

United States , Hong Kong , Li Jingjing , Zong Jiuyu , Zhang Zixuan , Wang Cunchuan , Ruby Hoo Lai Chong , Shu Lingling , Wu Xiaoping , Health Bureau , Key Laboratory Of Pharmaceutical Biotechnology , University Of Hong Kong Hkumed , Research Grants Council , Department Of Medicine , Technology Program , Collaborative Research Fund , Professor Of Department Pharmacology , Drug Administration , Department Of Pharmacology , Guangdong Pharmaceutical University , Sun Yat Sen University Cancer Center , Research Program , Professor Of The Department Pharmacology , Health Medical Research Fund , First Affiliated Hospital Of Jinan University , Assistant Professor ,