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Scientists harness naturally abundant CRISPR-Cas system to edit superbugs

Date Time
Scientists harness naturally abundant CRISPR-Cas system to edit superbugs
An illustration of the strategies and workflow of the transferrable type I CRISPR Cascade-mediated editing of the superbug P. aeruginosa.
A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong (HKU), reported the development of a transferrable and integrative type I CRISPR-based platform that can efficiently edit the diverse clinical isolates of Pseudomonas aeruginosa, a superbug capable of infecting various tissues and organs and a major source of nosocomial infections. The technique can accelerate the identification of resistance determinants of multidrug resistant (MDR) pathogens and the development of novel anti-resistance strategies. ....

Hong Kong , University Of Hong Kong , Hong Kong General , Aixin Yan , Li Ka Shing , Research Grants Council Of Hong Kong , Nucleic Acids Research , Research Division For Molecular Cell Biology , China Agricultural University , School Of Biological Sciences , Department Of Microbiology , Dr Meiru Si Qufu Normal University , Seed Fund For Basic Research , Research Fund , Associate Professor , Research Division , Cell Biology , Honorary Clinical Professor Patrick , Nucleic Acids , Queen Mary , Cell Reports , If Cascade , If Cascade Mediated , Biological Sciences , Postdoctoral Fellow , South China Agricultural University ,

HKU scientists harness the naturally abundant CRISPR-Cas system to edit superbugs with the hope of treating infections caused by drug resistant pathogens

HKU scientists harness the naturally abundant CRISPR-Cas system to edit superbugs with the hope of treating infections caused by drug resistant pathogens
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Hong Kong , University Of Hong Kong , Hong Kong General , Aixin Yan , Li Ka Shing , Research Grants Council Of Hong Kong , Nucleic Acids Research , Research Division For Molecular Cell Biology , China Agricultural University , School Of Biological Sciences , Department Of Microbiology , Dr Meiru Si Qufu Normal University , Seed Fund For Basic Research , Research Fund , Associate Professor , Research Division , Cell Biology , Honorary Clinical Professor Patrick , Nucleic Acids , Queen Mary , Cell Reports , If Cascade , If Cascade Mediated , Biological Sciences , Postdoctoral Fellow , South China Agricultural University ,

Naturally abundant venom peptide from ants can activate a pseudo allergic pathway unravelling a novel immunomodulatory pathway of MRGPRX2

Naturally abundant venom peptide from ants can activate a pseudo allergic pathway unravelling a novel immunomodulatory pathway of MRGPRX2
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Hong Kong , University Of Hong Kong , Hong Kong General , France General , Cindy Chan , European Regional Development Fund , Institut National Universitaire Champollion , Research Grants Council Of Hong Kong , Phrmasec Ltd , Linstitut National De La Sant , Research Team , Research Division For Molecular , European Union , Normandy University Rouen , Research Division , Cell Biology , Professor Michel , Professor Billy , Professor Chow , Research Grants Council , European Regional Development , National De La Sant , Normandy University , Region Normandy , External Relations Officer , Assistant Director ,

Discovery of ray sperms' unique swimming motion and demonstration with bio-inspired robot

It is generally agreed that sperms swim by beating or rotating their soft tails. However, a research team led by scientists from City University of Hong Kong (CityU) has discovered that ray sperms move by rotating both the tail and the head. The team further investigated the motion pattern and demonstrated it with a robot. Their study has expanded the knowledge on the microorganisms motion and provided inspiration for robot engineering design. ....

United States , Hong Kong , Shi Jiahai , Shen Yajing , Yang Xiong , Wang Panbing , National Science Foundation Of China , Tung Biomedical Sciences Center , Ocean Park Corporation Hong Kong , Research Grants Council Of Hong Kong , Hong Kong Health , Technology Innovation Fund , Professor Of The Department Biomedical Sciences , Cityu Department Of Biomedical Engineering , City University Of Hong Kong , High Energy Efficiency , Research Fund , City University , Associate Professor , Biomedical Engineering , Assistant Professor , Biomedical Sciences , National Academy , Dual Helixes , Energy Efficiency , Ocean Park Corporation Hong ,

Visionary bone damage study

Photo: Pixabay
A novel way to pinpoint and illuminate bone damage promises to make X-rays more efficient at diagnosing bone and other injuries, Flinders University researchers say.
The new technique, looking at potential biomedical applications of an ancient inorganic salt-based aggregation induced emission (AIE) radio-luminescence material, could open new frontiers in medicine including X-ray dosimetry, bioimaging and advanced applications such as optogenetics, says Professor Youhong Tang, from Flinders University’s College of Science and Engineering.
The research article, published by Professor Tang, postdoctoral researcher Dr Javad Tavokoli, colleagues in Hong Kong and Australian technology company Micro-X and, examined the potential of the AIEgen luminogens (AIEgens) in deep tissue imaging. The study used X-ray testing provided by Micro-X, a company based at the Tonsley Innovation District in Adelaide. ....

Hong Kong , New South Wales , Flinders University , South Australia , Yu Xiong , Zhaoxun Yu , Javad Tavokoli , Zheng Zhao , Tsz Shing Cheung , Xuepeng Zhang , Bolong Huang , Javad Tavakoli , Guogang Shan , Jianyu Zhang , Zaiyu Wang , Chen Peng , Youhong Tang , National Natural Science Foundation Of China , Research Grants Council Of Hong Kong , Technology Plan Of Shenzhen , Flinders University College Of Science , Technology Commission , Natural Science Foundation Of Guangdong Province , Professor Youhong Tang , Professor Tang , Tonsley Innovation District ,