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Top News In உடலியல் கோர் ஆராய்ச்சி பரப்பளவு தொழில்நுட்ப Today - Breaking & Trending Today

Nerve damage after chemo: potential risk factors revealed

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Being older, overweight and having low haemoglobin levels (fewer red blood cells) could increase a patient s risk of developing debilitating nerve damage following chemotherapy, a research team led by UNSW Sydney has revealed.
The researchers aimed to identify pre-treatment clinical and blood-based risk factors in patients who developed chemotherapy-induced peripheral neuropathy (CIPN) - nerve damage in peripheral body parts, like hands or feet, as a result of chemotherapy.
The study, published in
JAMA Network Open recently, examined patients - mostly women - who received paclitaxel or oxaliplatin chemotherapy treatment, which are common treatments for breast, colorectal and gynaecological cancers. ....

New South Wales , David Goldstein , David Mizrahi , Prince Of Wales Clinical School , Intestinal Trials Group , Cancer Institute , Medicine Health , University Of Sydney , Wales Clinical School , Professor David Goldstein , Conjoint Clinical Professor , Australasian Gastro Intestinal Trials Group , Associate Professor Susanna Park , Breast Cancer , Diet Body Weight , Health Care Systems Services , Health Professionals , Public Health , புதியது தெற்கு வேல்ஸ் , டேவிட் கோல்ட்ஸ்டைன் , டேவிட் மிஸ்ராஹி , ப்ரிந்ஸ் ஆஃப் வேல்ஸ் மருத்துவ பள்ளி , குடல் சோதனைகள் குழு , புற்றுநோய் நிறுவனம் , மருந்து ஆரோக்கியம் , பல்கலைக்கழகம் ஆஃப் சிட்னி ,

SRC-3 is a novel regulator of human immune T regulatory cells

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A study led by researchers at Baylor College of Medicine reveals a novel role of the steroid receptor coactivator 3 (SRC-3/NCOA3), a protein crucial for steroid hormone function and a prognostic marker for aggressive human breast and other cancers.
The team discovered that SRC-3 also regulates human immune T regulatory cells (Tregs), which contribute to the regulation of the body s immunological activity by suppressing the function of other immune cells, including those involved in fighting cancer. The study, which appears in the journal
Scientific Reports, shows that Tregs whose SRC-3 function was eliminated failed to suppress the activity of other immune cells in the lab. The authors anticipate that their findings may help in the fight against cancer in the future by leading to new approaches to inhibit Tregs activity which consequently would release immune attack in tumors. ....

Baylor College Of Medicine , United States , University Of Houston , Subhamoy Dasgupta , Prashi Jain , Neil Mckenna , Qin Feng , Bryan Nikolai , Bert Omalley , David Lonard , David Cardenas , Roswell Park Comprehensive Cancer Center , Brockman Foundation , Union Biometrica Biosorter , Baylor Danl Duncan Comprehensive Cancer Center , Research Institute Of Texas , Cancer Center Support Grant , Baylor College , Scientific Reports , Berto Malley , Danl Duncan Comprehensive Cancer Center , Danl Duncan Comprehensive Cancer , Brian York , Cancer Prevention , Research Institute , Facility Support Award ,

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders
Researchers from the Mitochondrial Medicine Frontier Program at Children s Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.
This preclinical research paves the way to develop more tailored treatment options for patients with inherited mitochondrial disease and acquired energy disorders. The findings emphasize the importance of rational therapeutic modeling to target specific cellular deficiencies and provide proper cellular nutrition as an effective means to manage mitochondrial disease.
The findings were published online by the journal
Human Molecular Genetics. ....

United States , Sujay Guha , Marni Falk , Neald Mathew , Emily Henderson , Division Of Human Genetics , Mitochondrial Medicine Frontier Program , Human Molecular , Study Senior Author , Human Genetics , Attending Physician , Executive Director , Mitochondrial Medicine , Mitochondrial Disease , Metabolic Disorders , ஒன்றுபட்டது மாநிலங்களில் , சுஜய் குஹா , மார்னி ஃபாக் , எமிலி ஹென்டர்சன் , பிரிவு ஆஃப் மனிதன் ஜெநெடிக்ஸ் , மைட்டோகாண்ட்ரியல் மருந்து எல்லை ப்ரோக்ர்யாம் , மனிதன் மூலக்கூறு , படிப்பு மூத்தவர் நூலாசிரியர் , மனிதன் ஜெநெடிக்ஸ் , கலந்துகொள்வது மருத்துவர் , நிர்வாகி இயக்குனர் ,

Dear Dietitian: Plateau

Dear Dietitian, ....

United States , Leanne Mccrate , Dear Dietitian , மிச Ou ரி , ஒன்றுபட்டது மாநிலங்களில் , அன்பே டயட்டீஷியன் ,

Changes in Human Hunting Practices May Explain Human Brain Development

How Less Or Zero Big Prey Sparked Human Brain Development
According to the scientists’ thesis , when early humans hunted the large animals they depended on for food into extinction, it toppled the first evolutionary domino.
At the time humans first appear in the fossil record (circa two million BC), the average size of land mammals was approximately 1100 pounds (500 kilograms). The earth was overrun with hulking creatures that were slow and easy to find, which meant the first human hunters didn’t have to travel very far or work very hard to keep their social groups well-fed.
Unfortunately for proto-man, the hunting was a little ....

H Efa , Tel Aviv , Miki Ben , Israel Tel Aviv University , Tel Aviv University , Miki Ben Dor , Ran Barkai , Adobe Stock , Deal With Climate Change , Could Our Brains Develop , Agricultural Revolution , Human Brain Development , Land Mammals , Cranial Capacity , ஏச் எபா , தொலைபேசி அவிவ் , மிகி பென் , இஸ்ரேல் தொலைபேசி அவிவ் பல்கலைக்கழகம் , தொலைபேசி அவிவ் பல்கலைக்கழகம் , மிகி பென் தோர் , ஒப்பந்தம் உடன் காலநிலை மாற்றம் , முடியும் அவர் மூளை உருவாக்க , மனிதன் மூளை வளர்ச்சி , நில பாலூட்டிகள் , க்ர்யாநியல் திறன் ,