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Microbial production of natural rainbow colorants


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IMAGE: Figure: Systems metabolic engineering was employed to construct and optimize the metabolic pathways and membrane engineering was employed to increase the production of the target colorants, successfully producing the seven.
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Credit: KAIST
A research group at KAIST has engineered bacterial strains capable of producing three carotenoids and four violacein derivatives, completing the seven colors in the rainbow spectrum. The research team integrated systems metabolic engineering and membrane engineering strategies for the production of seven natural rainbow colorants in engineered
Escherichia coli strains. The strategies will be also useful for the efficient production of other industrially important natural products used in the food, pharmaceutical, and cosmetic industries. ....

South Korea , Republic Of Korea , Dongsoo Yang , Rural Development Administration , Department Of Chemical , Seon Young Park , Distinguished Professor Sang Yup Lee , Advanced Science , Distinguished Professor Sang Yup , Research Program , Agriculture Science , Technology Development , Development Administration , Biomedical Environmental Chemical Engineering , Technology Engineering Computer Science , தெற்கு கொரியா , குடியரசு ஆஃப் கொரியா , துறை ஆஃப் இரசாயன , புகழ்பெற்ற ப்ரொஃபெஸர் பாடினார் ஆம் லீ , புகழ்பெற்ற ப்ரொஃபெஸர் பாடினார் ஆம் , ஆராய்ச்சி ப்ரோக்ர்யாம் , தொழில்நுட்பம் வளர்ச்சி , உயிர் மருத்துவ சுற்றுச்சூழல் இரசாயன பொறியியல் ,

Soft X-ray method promises nanocarrier breakthroughs for smart medicine


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IMAGE: Special X-ray colors resonate with bonds in molecules, (methyl is pictured in this illustration). This enables scientists to selectively probe chemically distinct parts of micelle nanocarriers in development for smart medicine.
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Credit: Washington State University
PULLMAN, Wash. - Before the huge potential of tiny nanocarriers for highly targeted drug delivery and environmental clean-up can be realized, scientists first need to be able to see them.
Currently researchers have to rely on attaching fluorescent dyes or heavy metals to label parts of organic nanocarrier structures for investigation, often changing them in the process. A new technique using chemically-sensitive soft X-rays offers a simpler, non-disruptive way of gaining insight into this nano-world. ....

Brian Collins , Washington State University , Nature Communications , Biomedical Environmental Chemical Engineering , Chemistry Physics Materials Sciences , Pharmaceutical Sciences , Medicine Health , Nanotechnology Micromachines , பிரையன் கோலின்ஸ் , வாஷிங்டன் நிலை பல்கலைக்கழகம் , இயற்கை தகவல்தொடர்புகள் , உயிர் மருத்துவ சுற்றுச்சூழல் இரசாயன பொறியியல் ,