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Microbial production of natural rainbow colorants


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IMAGE: Figure: Systems metabolic engineering was employed to construct and optimize the metabolic pathways and membrane engineering was employed to increase the production of the target colorants, successfully producing the seven.
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Credit: KAIST
A research group at KAIST has engineered bacterial strains capable of producing three carotenoids and four violacein derivatives, completing the seven colors in the rainbow spectrum. The research team integrated systems metabolic engineering and membrane engineering strategies for the production of seven natural rainbow colorants in engineered
Escherichia coli strains. The strategies will be also useful for the efficient production of other industrially important natural products used in the food, pharmaceutical, and cosmetic industries. ....

South Korea , Republic Of Korea , Dongsoo Yang , Rural Development Administration , Department Of Chemical , Seon Young Park , Distinguished Professor Sang Yup Lee , Advanced Science , Distinguished Professor Sang Yup , Research Program , Agriculture Science , Technology Development , Development Administration , Biomedical Environmental Chemical Engineering , Technology Engineering Computer Science , தெற்கு கொரியா , குடியரசு ஆஃப் கொரியா , துறை ஆஃப் இரசாயன , புகழ்பெற்ற ப்ரொஃபெஸர் பாடினார் ஆம் லீ , புகழ்பெற்ற ப்ரொஃபெஸர் பாடினார் ஆம் , ஆராய்ச்சி ப்ரோக்ர்யாம் , தொழில்நுட்பம் வளர்ச்சி , உயிர் மருத்துவ சுற்றுச்சூழல் இரசாயன பொறியியல் ,

Newly Engineered Bacterium can Produce Carminic Acid


Newly Engineered Bacterium can Produce Carminic Acid
Written by AZoMApr 7 2021
A team of researchers from the Korea Advanced Institute of Science and Technology (KAIST) has designed a bacterium that can produce carminic acid a natural red colorant that is extensively used in cosmetics and food.
A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering were employed to identify and improve the enzymes (DnrFP217K and GtCGTV93Q/Y193F) responsible for the latter two reactions. Image Credit: The Korea Advanced Institute of Science and Technology (KAIST).
The researchers have demonstrated the entire biosynthesis of carminic acid from glucose in a newly designed ....

United States , South Korea , Dae Jang , Dongsoo Yang , National Research Foundation , Journal Of The American Chemical Society , Generation Collaborative Lab , Department Of Chemical , Novo Nordisk Foundation , Korea Advanced Institute Of Science , Ministry Of Science , Korea Advanced Institute , Canary Islands , Woo Dae Jang , Distinguished Professor Sang Yup Lee , American Chemical Society , Postdoctoral Researcher , Hyup Lee , Distinguished Professor , Technology Development Program , Solve Climate Changes , Systems Metabolic Engineering , ஒன்றுபட்டது மாநிலங்களில் , தெற்கு கொரியா , டே ஜங் , தேசிய ஆராய்ச்சி அடித்தளம் ,

Microbial production of a natural red colorant carminic acid


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IMAGE: Figure: A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering was employed to identify and improve the enzymes (DnrFP217K.
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Credit: KAIST
A research group at KAIST has engineered a bacterium capable of producing a natural red colorant, carminic acid, which is widely used for food and cosmetics. The research team reported the complete biosynthesis of carminic acid from glucose in engineered Escherichia coli. The strategies will be useful for the design and construction of biosynthetic pathways involving unknown enzymes and consequently the production of diverse industrially important natural products for the food, pharmaceutical, and cosmetic industries. ....

United States , Dae Jang , Dongsoo Yang , National Research Foundation , Journal Of The American Chemical Society , Generation Collaborative Lab , Department Of Chemical , Novo Nordisk Foundation , Ministry Of Science , Canary Islands , Woo Dae Jang , Distinguished Professor Sang Yup Lee , American Chemical Society , Distinguished Professor Sang Yup , Technology Development Program , Solve Climate Changes , Systems Metabolic Engineering , Sangyup Lee , ஒன்றுபட்டது மாநிலங்களில் , டே ஜங் , தேசிய ஆராய்ச்சி அடித்தளம் , இதழ் ஆஃப் தி அமெரிக்கன் இரசாயன சமூகம் , ஜெநரேஶந் கூட்டு ஆய்வகம் , துறை ஆஃப் இரசாயன , அமைச்சகம் ஆஃப் அறிவியல் , கேனரி தீவுகள் ,