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Point of View: Open science takes on Parkinson's disease


Abstract
The Aligning Science Across Parkinson’s (ASAP) initiative was set up to improve understanding of the biology underlying the onset and progression of Parkinson’s disease. With an emphasis on open science and collaboration, we have assembled a research network led by nearly 100 investigators to explore the pathology of Parkinson’s disease, and this network will soon expand to include researchers working on relevant (dys)-functional neural circuits. We have also contributed to large-scale genetics and patient cohort initiatives related to the disease. We hope that these actions, and others planned for the future, will deepen our knowledge of the molecular mechanisms underlying the origin and evolution of Parkinson’s disease and, ultimately, contribute to the development of novel therapies. ....

United States , Shalini Padmanabhan , Chevy Chase , Todd Sherer , Michelle Durborow , Maggie Kuhl , Alyssa Reimer , Randy Schekman , University Of California , Parkinson Progression Markers Initiative , Global Parkinson Genetics Program , Medicines Partnership For Parkinson , Melinda Gates Foundation , Sergey Brin Family Foundation , Andrew Singleton National Institutes Of Health , Cure Parkinson , Planning Advisory Council , Collaborative Research Network , Parkinson Foundation , Department Of Molecular , Michaelj Fox Foundation For Parkinson Research , Kenneth Marek Institute For Neurodegenerative Disorders , Howard Hughes Medical Institute , Aligning Science Across Parkinson , Show Parkinson , Planning Advisory ,