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Air Pollution Exposure as a Kid May up Risk of Mental Illness Later

A multidecade study of young adults living in the united kingdom has found higher rates of mental illness symptoms among those exposed to higher levels of traffic-related air pollutants, particularly nitrogen oxides, during childhood and adolescence. ....

United Kingdom , Aaron Reuben , King Io , Helen Fisher , Human Development , Terms Of Service , United Kingdom Medical Research Council , Natural Environment Research Council , World Health Organization , United Kingdom National Atmospheric Emissions Inventory , Imperial College , Jacobs Foundation , Us National Institute Of Environmental Health Science , Scientist Office , King College London Institute Of Psychiatry , Us National Institute Of Child Health , Duke University , College London , Good Men Project , Child Health , Environmental Health Science , Chief Scientist Office , Together Multi , Interdisciplinary Research Scheme , Creative Commons , Premium Member ,

Damaged mitochondria activate autoimmunity suggests genome study

Damaged mitochondria activate autoimmunity suggests genome study
Appeared in BioNews 1095
Accumulation of defective mitochondria in cells may contribute to autoimmune conditions, such as Sjögren s syndrome, according to a recent study.
Researchers showed that mice lacking the
IRGM1gene showed similar autoimmune symptoms to patients with Sjögren s syndrome because they were not able to properly recycle their mitochondria. This left damaged parts of mitochondria in the cells, triggering an immune response against them.
Many autoimmune diseases exhibit increased type 1 interferon, said Dr Michael Fessler, senior author and head of the immunity, inflammation, and disease laboratory at the US National Institute of Environmental Health Sciences (NIEHS) in North Carolina. Our studies show how mitochondrial DNA that is not removed activates the immune system in mice and how it may happen in humans. ....

North Carolina , United States , Rosie Morley , Michael Fessler , Prashant Rai , Us National Institute Of Environmental Health Sciences , Environmental Health Sciences , வடக்கு கரோலினா , ஒன்றுபட்டது மாநிலங்களில் , ரோஸி மோர்லி , மைக்கேல் பெஸ்சிலேற் , பிரஷண்ட் ராய் , எங்களுக்கு தேசிய நிறுவனம் ஆஃப் சுற்றுச்சூழல் ஆரோக்கியம் அறிவியல் , சுற்றுச்சூழல் ஆரோக்கியம் அறிவியல் ,

Air pollution exposure as a kid may up risk of mental illness later

A multidecade study of young adults living in the United Kingdom has found higher rates of mental illness symptoms among those exposed to higher levels of traffic-related air pollutants, particularly nitrogen oxides, during childhood and adolescence.
Previous studies have identified a link between air pollution and the risk of specific mental disorders, including depression and anxiety, but this study looked at changes in mental health that span all forms of disorder and psychological distress associated with exposure to traffic-related air pollutants.
The findings reveal that the greater an individual’s exposure to nitrogen oxides across childhood and adolescence, the more likely they are to show any signs of mental illness at the transition to adulthood, at age 18, when most symptoms of mental illness have emerged or begin to emerge. ....

United Kingdom , Aaron Reuben , King Io , Helen Fisher , Human Development , United Kingdom Medical Research Council , Natural Environment Research Council , United Kingdom National Atmospheric Emissions Inventory , World Health Organization , Imperial College , Jacobs Foundation , Us National Institute Of Environmental Health Science , Scientist Office , King College London Institute Of Psychiatry , Us National Institute Of Child Health , Duke University , College London , Child Health , Environmental Health Science , Chief Scientist Office , Together Multi , Interdisciplinary Research Scheme , ஒன்றுபட்டது கிஂக்டம் , ஆரோன் ரூபன் , கிங் ஐயொ , ஹெலன் மீனவர் ,

Metformin may affect risk of breast cancer in women with type 2 diabetes

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A study of 44,541 women has found that there appears to be no association between type 2 diabetes and developing breast cancer overall. This may be because most women in the study with type 2 diabetes were taking metformin, a medication widely used to treat type 2 diabetes, whose actions may help to reduce the risk of developing oestrogen positive (ER-positive) breast cancer.
ER-positive breast cancer (cancer that has receptors on cell surfaces for the hormone oestrogen) accounts for about 80% of breast cancer diagnosed in the USA. Associations uncovered in the study suggested that the link between type 2 diabetes and breast cancer varied by breast cancer subtype and was affected by the use of metformin to treat diabetes. The study is published in the leading cancer journal ....

Puerto Rico , United States , Dale Sandler , Pamela Goodwin , Us National Institute Of Environmental Health Sciences , University Of Toronto , Epidemiology Branch , University Of Western Ontario , National Institutes Of Health United States , University Of Arkansas , Environmental Health Sciences , National Institutes , Sister Study , Medical Sciences , Western Ontario , Medicine Health , Breast Cancer , Diet Body Weight , Metabolism Metabolic Diseases , ப்வெர்டோ ரிக்கோ , ஒன்றுபட்டது மாநிலங்களில் , டேல் சாண்ட்லர் , பமீலா குட்வின் , எங்களுக்கு தேசிய நிறுவனம் ஆஃப் சுற்றுச்சூழல் ஆரோக்கியம் அறிவியல் , பல்கலைக்கழகம் ஆஃப் டொராண்டோ , தொற்றுநோய் கிளை ,

PFAS exposure found to increase risk of severe Covid-19

By Rebecca Trager2021-01-12T14:30:00+00:00
Toxicologists are expressing concern that exposure to per- or poly-fluorinated substances (PFASs) can increase a person’s likelihood of developing severe Covid-19. There are also warning that PFASs could also diminish the effectiveness of a vaccine against the novel coronavirus.
A number of studies in the scientific literature have now linked elevated PFAS levels with immune system suppression, as well as decreased response to vaccines. Philippe Grandjean, an adjunct environmental health professor at Harvard University, and colleagues have found that higher levels of the PFAS perfluorobutanoic acid (PFBA) in the blood are associated with increased severity of Covid-19 infections. ....

United States , Northwestern University , Philippe Grandjean , Linda Birnbaum , Jamie Dewitt , Us National Institute Of Environmental Health Sciences , Carolina University , Harvard University , National Toxicology Program , Environmental Working Group , Us Centers For Disease , Will Dichtel , Disease Control , Environmental Health Sciences , East Carolina University , ஒன்றுபட்டது மாநிலங்களில் , வடமேற்கு பல்கலைக்கழகம் , பிலிப் கிரன்தஜிெஅன் , லிண்டா பிர்ன்பாம் , ஜேமி டேவிட்ட , எங்களுக்கு தேசிய நிறுவனம் ஆஃப் சுற்றுச்சூழல் ஆரோக்கியம் அறிவியல் , கரோலினா பல்கலைக்கழகம் , ஹார்வர்ட் பல்கலைக்கழகம் , தேசிய நச்சுயியல் ப்ரோக்ர்யாம் , சுற்றுச்சூழல் வேலை குழு , எங்களுக்கு மையங்கள் க்கு நோய் ,