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LYNPARZA® (olaparib) reduced the risk of cancer recurrence by 42% in the adjuvant treatment of patie

First medicine targeting BRCA mutations to show clinical benefit in adjuvant settingWILMINGTON, Del. (BUSINESS WIRE) AstraZeneca and Merck & Co., Inc., known as MSD outside the US and Canada, today announced results from the OlympiA Phase III trial showed LYNPARZA® (olaparib) demonstrated a statistically significa. ....

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Investegate |AstraZeneca PLC Announcements | AstraZeneca PLC: Lynparza reduced recurrence risk in breast cancer

Investegate announcements from AstraZeneca PLC, Lynparza reduced recurrence risk in breast cancer ....

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Lynparza shows promise in preventing cancer recurrence

Lynparza is the first medicine targeting BRCA mutations to show clinical benefit in adjuvant setting - News - PharmaTimes ....

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Financial barriers to accessing preventative care for breast cancer detailed in new study

Even though Kati Wolfgang had help and insurance it wasn’t easy.
After two of her aunts developed breast cancer by the age of 34, her father got tested to see if he carried the BRCA gene, a mutation that substantially elevates the risk of developing breast and ovarian cancers.
His results came back positive, opening the door for genetic counseling for Wolfgang and her three sisters when she was just 18. By the time she was 28, she had spent a decade doing annual ultrasounds and MRIs to monitor whether cancer had developed in her breast tissue.
By then, she was ready to have a preventive mastectomy. ....

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FDA grants accelerated approval for GSK's JEMPERLI (dostarlimab-gxly) for women with recurrent or advanced dMMR endometrial cancer

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LONDON, April 22, 2021 /PRNewswire/ GlaxoSmithKline plc (LSE/NYSE: GSK) today announced that the US Food and Drug Administration (FDA) has approved JEMPERLI (dostarlimab-gxly), a programmed death receptor-1 (PD-1) blocking antibody, based on the company s Biologics License Application. JEMPERLI is indicated for the treatment of adult patients with mismatch repair-deficient (dMMR) recurrent or advanced endometrial cancer, as determined by an FDA-approved test, that have progressed on or following prior treatment with a platinum-containing regimen. This indication is approved under accelerated approval based on tumor response rate and durability of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). ....

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