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Two regions in the canine genome explain one third of the risk of rare blood cancer


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Mutations in two genetic regions in dogs explain over one third of the risk of developing an aggressive form of hematological cancer, according to a study led by Jacquelyn Evans and Elaine Ostrander at the National Human Genome Research Institute in Maryland, USA and colleagues. The study, which combined multiple sequencing techniques to investigate histiocytic sarcoma in retriever dogs, publishes May 13 in the open-access journal
PLOS Genetics.
Histiocytic sarcoma is an aggressive cancer of immune cells, and although extremely rare in humans, it affects around one-in-five flat-coated retrievers. Genome-wide association surveys of 177 affected and 132 unaffected flat-coated retrievers identified two loci on chromosomes 5 and 19 of the canine genome associated with histiocytic sarcoma. Whole genome, transcriptome, and chromatin immunoprecipitation (CHiP) sequence data revealed that the CFA5 locus contains mutations near a known tumor-suppressor gene, PIK3R ....

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Why Do Dogs Age Faster Than Cats? | POPSUGAR Pets


Dogs May Look Like They re Aging Faster Than Cats, but That s Not Actually the Case!
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Dogs are man s best friend. More so than cats, they aim to please, they mimic human behavior and they love to hang out with their owners. They re so similar to their pet parents that they even age similarly to humans, according to a study by researchers at the National Institutes of Health.
Dogs experience the same biological hallmarks of aging as humans, but do so in a compressed period, around 10 to 15 years on average, versus over 70 years in humans, said Elaine Ostrander, National Institutes of Health distinguished investigator and co-author of the paper, in a release. ....

Elaine Ostrander , Jennifer Freeman , Getty Justin Paget , Michelle Lugones , National Institutes Of Health , Friends Animal Society , National Institutes , Visual Signs , Best Friends Animal , Great Dane , Cats Dont Age , எலைன் ஒஸ்திறாந்டேர் , ஜெனிபர் ஃப்ரீமேன் , கெட்டி ஜஸ்டின் பேஜி , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , நண்பர்கள் விலங்கு சமூகம் , தேசிய நிறுவனங்கள் , காட்சி அறிகுறிகள் , சிறந்தது நண்பர்கள் விலங்கு , நன்று டேன் , பூனைகள் டோன்ட் வாழ்நாள் ,

Dogs May Look Like They're Aging Faster Than Cats, But That's Not Actually the Case!


Dogs May Look Like They re Aging Faster Than Cats, but That s Not Actually the Case!
PopSugar
2/19/2021
Kathryn Mayer
© Getty / Justin Paget
Dogs May Look Like They re Aging Faster Than Cats, but That s Not Actually the Case!
Dogs are man s best friend. More so than cats, they aim to please, they mimic human behavior and they love to hang out with their owners. They re so similar to their pet parents that they even age similarly to humans, according to a study by researchers at the National Institutes of Health.
Dogs experience the same biological hallmarks of aging as humans, but do so in a compressed period, around 10 to 15 years on average, versus over 70 years in humans, said Elaine Ostrander, National Institutes of Health distinguished investigator and co-author of the paper, in a release. ....

Elaine Ostrander , Jennifer Freeman , Getty Justin Paget , Michelle Lugones , National Institutes Of Health , Friends Animal Society , Not Actually , National Institutes , Visual Signs , Best Friends Animal , Great Dane , Cats Dont Age , எலைன் ஒஸ்திறாந்டேர் , ஜெனிபர் ஃப்ரீமேன் , கெட்டி ஜஸ்டின் பேஜி , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , நண்பர்கள் விலங்கு சமூகம் , இல்லை உண்மையில் , தேசிய நிறுவனங்கள் , காட்சி அறிகுறிகள் , சிறந்தது நண்பர்கள் விலங்கு , நன்று டேன் , பூனைகள் டோன்ட் வாழ்நாள் ,