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Higher rates of chronic pain in women linked to genetics


Credit: Esther Max, Flickr. Rotated from original.
Women may be at greater risk of experiencing chronic pain because the condition has a different genetic basis in men and women. Keira Johnston of the University of Glasgow and colleagues report these findings in a new study published April 8th in
PLOS Genetics.
Chronic pain is a common and potentially debilitating condition that tends to affect more women than men. To explore this disparity, researchers undertook the largest ever genetic study of chronic pain that analyzed women and men separately. They looked for genetic variants associated with chronic pain in 209,093 women and 178,556 men, and compared the results. In women, 31 genes were associated with chronic pain, while 37 genes were linked in men. A single gene was associated with chronic pain in both sexes. The researchers also investigated whether the activity of these genes was turned up or down in tissues known to be related to chronic pain. They found th ....

Keira Johnston , Royal College Of Physicians Edinburgh , Mental Health Data Pathfinder Award , Wellcome Trust Grant , Doctoral Training Programme Studentship , University Of Glasgow , National Institute Of Neurological Disorders , United Kingdom , United Kingdom Fellowship , Royal College , Training Programme Studentship , Lister Prize Fellowship , Health Data Pathfinder Award , Pathfinder Award , National Institute , Neurological Disorders , அரச கல்லூரி ஆஃப் மருத்துவர்கள் எடின்பர்க் , மன ஆரோக்கியம் தகவல்கள் பாத்ஃபைண்டர் விருது , வெல்கம் நம்பிக்கை மானியம் , பல்கலைக்கழகம் ஆஃப் கிளாஸ்கோ , தேசிய நிறுவனம் ஆஃப் நரம்பியல் கோளாறுகள் , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது கிஂக்டம் கூட்டுறவு , அரச கல்லூரி , பாத்ஃபைண்டர் விருது , தேசிய நிறுவனம் ,

Registration, Abstract Submission Open for CCTS Spring Research Days


Feb. 24, 2021
LEXINGTON, Ky.
(Feb. 24, 2021) The University of Kentucky Center for Clinical and Translational Science (CCTS) will host the acclaimed medical historian John M. Barry, author of The Great Influenza: The Story of the Deadliest Pandemic in History, at the keynote panel of its 2021 Spring Research Days. The free, virtual event will be held on the afternoons of April 7 and 8.
Held in conjunction with the UK College of Dentistry, the UK College of Nursing, and the Implementation Science Research Day, the CCTS Spring Research Days will focus on sharing research findings and best practices, enhancing collaborations, and mentoring the upcoming generation of clinical and translational researchers. This year’s new virtual format will feature an interactive conference space, where you might even find cartoon caption tests and a science comic book reveal. ....

New York , United States , United Kingdom , Claire Clark , Johnm Barry , Allmen Allman , Karen Petrone , Lovoria Williams , United Kingdom College Of Nursing , Tulane School Of Public Health , World Health Organization , United Kingdom College Of Medicine , United Nations , United Kingdom Cooperative For The Humanities , Scholar At Tulane Bywater Institute , Spring Research Days , Implementation Science Research Day , New York Times , National Academies Of Sciences , United Kingdom College Of Dentistry , University Of Kentucky , Translational Science , Great Influenza , Deadliest Pandemic , United Kingdom College , Research Days ,