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Ultra-high Field MRI Detects Subtle Differences of Brain's 'Hippocampus' in People with Down Syndrome

Ultra-high Field MRI Detects Subtle Differences of Brain’s ‘Hippocampus’ in People with Down Syndrome
Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus a region of the brain tied to memory and learning.
April 29, 2021 Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus a region of the brain tied to memory and learning. ....

James Leverenz , Stephen Ruedrich , H Gerry Taylor , Z Irene Wang , Alberto Costa , L Douglas Lenkoski , Katherine Koenig , Elizabeth Roth , Neurological Research , School Of Medicine , University Hospitals , Ohio State University , National Institute On , Brain Communications , University Hospitals Cleveland Medical Center , Brain Health , Department Of Psychiatry At Case Western , Alzheimer Association , Neurological Institute , Biobehavioral Health , Department Of Biomedical Engineering , Case Western Reserve University School Of Medicine , Hankuk University Of Foreign , Cleveland Lou Ruvo Center , Alana United States Foundation , Angels Foundation ,

Ultra-high field MRI detects differences in brain's 'hippocampus'

Ultra-high field MRI detects differences in brain's 'hippocampus'
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

James Leverenz , Stephen Ruedrich , H Gerry Taylor , Z Irene Wang , Alberto Costa , L Douglas Lenkoski , Melissa Stasko , Katherine Koenig , Elizabeth Roth , Neurological Research , School Of Medicine , University Hospitals , Ohio State University , National Institute On , Brain Communications , University Hospitals Cleveland Medical Center , Brain Health , Department Of Psychiatry At Case Western , Alzheimer Association , Neurological Institute , Biobehavioral Health , Department Of Biomedical Engineering , Case Western Reserve University School Of Medicine , Hankuk University Of Foreign , Cleveland Lou Ruvo Center , Alana United States Foundation ,

Potential Blood Biomarker for TBI, and Mechanistic Link with Alzheimer's Disease Identified

Potential Blood Biomarker for TBI, and Mechanistic Link with Alzheimerâs Disease Identified
April 15, 2021
Source: Moussa81/Getty Images
Scientists headed by a team at the Harrington Discovery Institute have discovered a potential new approach to preventing brain nerve cells from deteriorating after brain injury. The teamâs work, reported in
Cell, demonstrated that traumatic brain injury (TBI) induces acetylation of the tau protein at sites that are also acetylated in human Alzheimerâs disease (AD), and revealed a potential mechanistic link between TBI and AD. The studies in addition indicated that blood levels of acetylated tau (ac-tau) could represent a potential biomarker for TBI. Strikingly, the researchers found that two FDA-approved NSAID (nonsteroidal anti-inflammatory drug) medicines, salsalate and diflunisal, were potently neuroprotective after TBI in mice, while an analysis of human records indicated that use of either drug for other indi ....

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Researchers discover a new way to prevent brain nerve cells from deteriorating after injury

Researchers discover a new way to prevent brain nerve cells from deteriorating after injury
Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with some form of chronic impairment after suffering a TBI. Even in a mild form, TBI can lead to lifelong nerve cell deterioration associated with a wide array of neuropsychiatric conditions. Tragically, there are no medicines to protect nerve cells after injury. Behind aging and genetics, TBI is the third leading cause of Alzheimer s disease (AD), yet the link between these two conditions is not understood. ....

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Researchers discover new way to monitor & prevent nerve cell deterioration after TBI

Researchers discover new way to monitor & prevent nerve cell deterioration after TBI
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

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