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New drug combination discovery makes curative surgery possible for liver cancer patients


New drug combination discovery makes curative surgery possible for liver cancer patients
ANI |
Updated: Jul 30, 2021 11:53 IST
Maryland [US], July 30 (ANI): During a recent study, researchers found that a combination of the immunotherapy drug nivolumab and the kinase-inhibitor drug cabozantinib can make curative surgery possible in some liver cancer patients who would normally not be considered surgical candidates.
Results published in the journal Nature Cancer by researchers at the Johns Hopkins Kimmel Cancer Center describe the benefits of this drug combination.
Among 15 people with hepatocellular carcinoma (HCC) in the study who could not be treated previously with surgery, the drugs allowed 12 patients to undergo successful surgical removal of their cancer. Five of these 12 patients had only 10 per cent or less of their tumour remaining after the drug treatment. ....

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Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy


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IMAGE: The AstroPath platform allows for the assessment of the level of expression of a given marker on individual cells, while maintaining information on their spatial location. Shown here is.
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Credit: Seyoun Park, Ph.D.
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
A new platform, called AstroPath, melds astronomic image analysis and mapping with pathology specimens to analyze microscopic images of tumors. ....

United States , Janis Taube , Charles Roberts , Evanj Lipson , Richard Wilton , Shlomit Jessel , Harriet Kluger , Evan Lipson , Inbalb Sander , Peter Nguyen , Jose Loyola , Qingfeng Zhu , Akoya Biosciences , Michele Cleary , Robert Anders , Suzannel Topalian , Elizabethm Jaffee , Ludmila Danilova , Elizabeth Engle , Margaret Eminizer , Daphne Wang , Sneha Berry , Aleksandra Ogurtsova , Angelo Demarzo , Haiying Xu , Roberta Anders ,

NCI-designated cancer centers call for action to get HPV vaccination back on track


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IMAGE: HPV infection causes cells to undergo changes. If not treated these cells can, over time, become cancer cells.
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Credit: National Cancer Institute
Today, doctors and scientists across America at National Cancer Institute (NCI)-designated cancer centers and other organizations issued a joint statement urging the nation s health care systems, physicians, parents and children, and young adults to get the human papillomavirus (HPV) vaccination back on track.
Dramatic drops in annual well visits and immunizations during the COVID-19 pandemic have caused a significant vaccination gap and lag in vital preventive services among U.S. children and adolescents especially for the HPV vaccine. The pandemic also has exacerbated health disparities, leaving Black, Indigenous and other people of color; rural; and sexual minority adolescents at even greater risk for missed doses of this cancer prevention vaccine. ....

United States , San Antonio , Vanderbilt Ingram Cancer Center , Wake Forest Baptist Health Comprehensive Cancer Center , Winship Cancer Institute Of Emory University , Lineberger Comprehensive Cancer Center , Fred Hutchinson Cancer Research Center , Knight Cancer Institute , University Of Hawaii Cancer Center , Centers For Disease , University Of Texas Md Anderson Cancer Center , Hitchock Norris Cotton Cancer Center , Barbara Ann Karmanos Cancer Institute , Fred Pamela Buffett Cancer Center , American Association For Cancer Research , Koch Institute For Integrative Cancer Research , Georgetown Lombardi Comprehensive Cancer Center , Cold Spring Harbor Laboratory Cancer Center , Hillman Cancer Center , Wistar Institute Cancer Center , Sanford Burnham Prebys Cancer Center , Cancer Centers , American Society Of Clinical Oncology , Sidney Kimmel Cancer Center , Haroldc Simmons Comprehensive Cancer Center , Rutgers Cancer Institute Of New Jersey ,

Sidney Kimmel Cancer Center at Jefferson Health Joins Caris Life Sciences Precision Oncology Alliance


National Cancer Institute-designated Sidney Kimmel Cancer Center partners with Caris’ collaborative network of oncology experts to advance personalized cancer treatments
IRVING, Texas, May 14, 2021
– Caris Life Sciences®, a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine, announced today that the Sidney Kimmel Cancer Center – Jefferson Health (SKCC) has joined Caris’ Precision Oncology Alliance™ (POA). The POA is a collaborative network of leading cancer centers that work together to advance comprehensive cancer profiling and establish standards of care for molecular testing in oncology through research focused on predictive and prognostic markers that improve the clinical outcomes of patients with cancer. ....

New York , United States , Chadi Nabhan , Brianj Brille , Karene Knudsen , Lindsey Bailys , Lauren Riley , Caris Codeai , Caris Pharmatech , Time Clinical Trial Solutions , National Cancer Institute , Caris Life Sciences Media Contact , Sidney Kimmel Cancer Center , National Cancer Sidney Kimmel Center , Jefferson Health Media Contact , Precision Oncology Alliance , Jefferson Health , Cari Precision Oncology Alliance , Oncology Network , Caris Life Sciences , Oncology Services , Caris Precision Oncology Alliance , Cancer Institute , Greater Philadelphia , Enterprise Director , Caris Precision Oncology ,