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Researchers identify kite-shaped molecules that block SARS-CoV-2 cell entry after attachment

Researchers identify kite-shaped molecules that block SARS-CoV-2 cell entry after attachment
A team of scientists from the University of Manchester, UK, has recently screened a panel of FDA-approved compounds to identify potential antiviral agents against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19). They have identified a group of kite-shaped compounds that are highly specific to SARS-CoV-1 and SARS-CoV-2. These compounds demonstrate high potency in inhibiting SARS-CoV-2 infection at early entry steps. The study is currently available on the
Background
As of June 2, 2021, globally, there have been more than 171 million confirmed SARS-CoV-2 infections, with over 3.56 million deaths. The newly emerging viral variants have led to global concerns about the long-term efficacy of the COVID-19 vaccines that have been developed against the original strain of SARS-CoV-2. In order to effectively con ....

United Kingdom , Sanchari Sinha Dutta , Shuttterstock Sars Co , University Of Manchester , Corona Borealis Studio , Image Credit , Cat Don , Middle East , Coronavirus Disease Covid 19 , Ars Cov 2 , Ngiotensin Converting Enzyme 2 , Ers Cov , Reporter Gene , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein , ஒன்றுபட்டது கிஂக்டம் , சஞ்சரி சீன்ஹா தத்தா , பல்கலைக்கழகம் ஆஃப் மான்செஸ்டர் , கொரோனா போரியாலிஸ் ஸ்டுடியோ , படம் கடன் , நடுத்தர கிழக்கு ,

Which biomarkers can help predict adverse outcomes in COVID-19?

Which biomarkers can help predict adverse outcomes in COVID-19?
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of coronavirus disease 2019 (COVID-19), was declared a pandemic on March 11, 2020, by the World Health Organisation (WHO).
The severity of this infectious disease has strained healthcare resources to capacity in many parts of the world. Many healthcare systems have seen an inadequate number of intensive care unit (ICU) beds as well as mechanical ventilators available to treat the influx of patients the pandemic has wrought. The critically low supply of these vital resources underscores the need for clinicians to identify biomarkers that can predict factors such as ICU stay and mortality. This would help to allocate these lifesaving resources appropriately. ....

United States , Marzia Khan , Marzia Khanmay , Tongji Hospital Of Huazhong University Science , Journal Of Clinical Medicine Research , World Health Organisation , Coronavirus Disease , Image Credit , Corona Borealis Studio , Clinical Medicine , Tongji Hospital , Huazhong University , Jinyintan Hospital , Wuhan Pulmonary Hospitals , Coronavirus Disease Covid 19 , Ars Cov 2 , D Dimer , Intensive Care , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , இதழ் ஆஃப் மருத்துவ மருந்து ஆராய்ச்சி , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , படம் கடன் , கொரோனா போரியாலிஸ் ஸ்டுடியோ , மருத்துவ மருந்து ,

Novel broad-spectrum antiviral compounds effective against Zika and SARS-CoV-2

A research team at the University of Alberta, Canada, led by Dr. Daniel Limonta, has described two novel molecules with broad antiviral properties that are effective against a range of virus types, including SARS-CoV-2. ....

United States , Michael Burgess , Michael Burgessmay , Daniel Limonta , American Society For Microbiology , University Of Alberta , Corona Borealis Studio , American Society , Coronavirus Disease Covid 19 , Ars Cov 2 , Antiviral Drug , Immune Response , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Yellow Fever , Zika Virus , ஒன்றுபட்டது மாநிலங்களில் , மைக்கேல் பர்கஸ் , அமெரிக்கன் சமூகம் க்கு நுண்ணுயிரியல் , பல்கலைக்கழகம் ஆஃப் ஆல்பர்ட்டா , கொரோனா போரியாலிஸ் ஸ்டுடியோ , அமெரிக்கன் சமூகம் ,

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France

SARS-CoV-2 B.1.1.420 and B.1.617.1 immune escape variants reported in France
Since its emergence in Wuhan, China, in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 (coronavirus disease 2019), is rapidly spreading, with numerous variants being observed around the world. A high transmission rate would indicate an undergoing process of positive selection of variants, which might allow the virus to acquire some advantageous genetic traits. Emerging variants are likely to be more transmissible, more pathogenic, and more likely to escape natural immunity or vaccine immunity.
Therefore genomic surveillance of SARS-CoV-2 and its variants is essential. It provides insights into the mechanisms behind viral dissemination worldwide. The variants include N501Y, E484K, or L452R mutations on gene coding to the viral spike protein. The two new Indian variants recently identified are N440K and the E484Q and L452R mutations assoc ....

Ramya Dwivedi , Image Credit , Corona Borealis Studio , Ars Cov 2 , Coronavirus Disease Covid 19 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein , ரம்யா டுவிவேடி , படம் கடன் , கொரோனா போரியாலிஸ் ஸ்டுடியோ ,

Antibody response following SARS-CoV-2 mRNA vaccine is greater than natural infection

Antibody response following SARS-CoV-2 mRNA vaccine is greater than natural infection
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

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