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COVID-19 virus triggers antibodies from previous coronavirus infections: Study


The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.
Image/Dr. Fred Murphy & Sylvia Whitfield/CDC
COVID-19 isn’t humanity’s first encounter with a coronavirus, so named because of the corona, or crown-like, protein spikes on their surface. Before SARS-CoV-2 the virus that causes COVID-19 humans have navigated at least 6 other types of coronaviruses.
The study sought to understand how coronaviruses (CoVs) ignite the human immune system and conduct a deeper dive on the inner workings of the antibody response. The published findings, “Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses,” appear  in the journal ....

Saudi Arabia , Jason Ladner , John Altin , Zane Fink , City Of Hope National Medical Center , Northern Arizona University , Translational Genomics Research Institute Tgen , Sanford Burnham Prebys Medical Discovery Institute , University Of Illinois , Vitalant Research Institute , Walter Reed National Military Medical Center , Microbiome Institute , Encodia Inc , Norwegian University Of Science , Translational Genomics Research Institute , Cell Reports , Middle East Respiratory Syndrome , Severe Acute Respiratory , Hope National Medical Center , Norwegian University , Olavs Hospital , சவுதி அரேபியா , ஜேசன் லாட்னேற் , ஜான் அல்டின் , ஜேன் ஃபிங்க் , நகரம் ஆஃப் நம்பிக்கை தேசிய மருத்துவ மையம் ,

Tracking cancer metastasis with CRISPR opens new areas for drug development


Jan 22, 2021 8:52am
Using CRISPR gene-editing technology, scientists were able to map out phylogenetic trees that track the lineage of individual cancer cells as they proliferate and metastasize. (Jeffrey Quinn/Whitehead Institute)
Metastasis is responsible for most cancer-related deaths, but it’s hard to trace. Now, a group of researchers has developed a CRISPR-based method that helped track tumor spreading patterns.
Researchers from the Massachusetts Institute of Technology (MIT), the University of California, Berkeley and the University of California, San Francisco used the CRISPR gene editing tool to map out a detailed family tree that revealed the dynamics behind the development and progression of cancer metastases. ....

United States , San Francisco , Jonathan Weissman , University Of California , Massachusetts Institute Of Technology , Fred Hutchinson Cancer Research Center , Sanford Burnham Prebys Medical Discovery Institute , Massachusetts Institute , Professor Jonathan Weissman , ஒன்றுபட்டது மாநிலங்களில் , சான் பிரான்சிஸ்கோ , ஜொனாதன் வெயிஸ்மேன் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , மாசசூசெட்ஸ் நிறுவனம் ஆஃப் தொழில்நுட்பம் , ஃப்ரெட் ஹட்சின்சன் புற்றுநோய் ஆராய்ச்சி மையம் , சான்ஃபோர்ட் பர்ன்ஹாம் பிரேபய்ச் மருத்துவ கண்டுபிடிப்பு நிறுவனம் , மாசசூசெட்ஸ் நிறுவனம் , ப்ரொஃபெஸர் ஜொனாதன் வெயிஸ்மேன் ,

Study results show COVID-19 virus triggers antibodies from previous coronavirus infections


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The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.
COVID-19 isn t humanity s first encounter with a coronavirus, so named because of the corona, or crown-like, protein spikes on their surface. Before SARS-CoV-2 the virus that causes COVID-19 humans have navigated at least 6 other types of coronaviruses.
The study sought to understand how coronaviruses (CoVs) ignite the human immune system and conduct a deeper dive on the inner workings of the antibody response. The published findings, Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses, appear today in the journal Cell Reports Medicine. ....

United States , Saudi Arabia , Northern Arizona University , Steve Yozwiak , Jason Ladner , John Altin , Zane Fink , City Of Hope National Medical Center , Translational Genomics Research Institute Tgen , National Institutes Of Health , Sanford Burnham Prebys Medical Discovery Institute , University Of Illinois , Research Initiative Fund , Vitalant Research Institute , Arizona Technology , Walter Reed National Military Medical Center , Microbiome Institute , Encodia Inc , Norwegian University Of Science , Translational Genomics Research Institute , Cell Reports , Middle East Respiratory Syndrome , Severe Acute Respiratory , Hope National Medical Center , Norwegian University , Olavs Hospital ,