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Multiple myeloma is a common hematological malignancy that has its origins in plasma cells. Despite treatment becoming more sophisticated, there is still currently no cure. However, immunotherapy targeting CD38/CD3 is proving to be very promising. ....
The NKG2 protein family is mostly expressed on cytotoxic immune cells. They have emerged as new and exciting targets for the development of immune checkpoint modulators in immunotherapy. ....
NKG2 ligands for immune checkpoint modulator research : Get Quote, RFQ, Price or Buy news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
A new study by a team of researchers at the Keck School of Medicine, University of Southern California, USA, reports a potentially important therapeutic target in the form of a molecule called GRP78 that promotes the entry and protein production by many viruses. The team's paper has been published in the Journal of Biological Chemistry. ....
CAR-T Therapy: Combating Cytokine Release Syndrome Sponsored Content by ACROBiosystemsMay 21 2021 CAR-T cell therapy offers the hope of a cure to a number of cancer patients. Yet, in spite of the great effectiveness, more attention has been paid to the toxicity of the therapy known as cytokine release syndrome (CRS). This article is aimed at summarizing the main points of assessment, grading and management of CRS in CAR-T Therapy and provide answers to the following questions: How to identify the onset of CRS clinically? What is CRS management? How to use tocilizumab in CRS management？ Assessment, grading and management of CRS in CAR-T therapy ....