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Cold sores: Discovery reveals how stress, illness and even sunburn trigger flareups


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IMAGE: Researchers Sean R. Cuddy and Anna R. Cliffe of the University of Virginia School of Medicine have shed light on what causes cold sores to flare up. The discovery could.
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Credit: Courtesy Cliffe lab at UVA
Researchers at the University of Virginia School of Medicine have shed light on what causes herpes simplex virus to flare up, explaining how stress, illness and even sunburn can trigger unwanted outbreaks.
The discovery could lead to new ways to prevent cold sores and herpes-related eye disease from reoccurring, the researchers report.
Herpes simplex recurrence has long been associated with stress, fever and sunburn, said researcher Anna R. Cliffe, PhD, of UVA s Department of Microbiology, Immunology and Cancer Biology. This study sheds light on how all these triggers can lead to herpes simplex-associated disease. ....

United States , Amina Farah , Jon Suzich , Bimaln Desai , Philipv Seegren , Seanr Cuddy , Chris Boutell , Parijat Kundu , Sara Dochnal , Austinr Schinlever , Department Of Microbiology , National Eye Institute , National Institute Of Allergy , Research Council , University Of Virginia School Medicine , National Institute , Virginia School , National Institutes , Neurological Disorder , Infectious Diseases , General Medical Sciences , Medical Research Council , Medicine Health , Immunology Allergies Asthma , Infectious Emerging Diseases , Public Health ,

Biomarkers in mother's plasma predict a type of autism in offspring with 100% accuracy


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Using machine learning, researchers at the UC Davis MIND Institute have identified several patterns of maternal autoantibodies highly associated with the diagnosis and severity of autism.
Their study, published Jan. 22 in
Molecular Psychiatry, specifically focused on maternal autoantibody-related autism spectrum disorder (MAR ASD), a condition accounting for around 20% of all autism cases.
The implications from this study are tremendous, said Judy Van de Water, a professor of rheumatology, allergy and clinical immunology at UC Davis and the lead author of the study. It s the first time that machine learning has been used to identify with 100% accuracy MAR ASD-specific patterns as potential biomarkers of ASD risk. ....

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Snake sex chromosomes say less about sex and more about survival


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IMAGE: Researchers studied the genes on the sex-specific chromosomes of three species of snakes, including the five-pacer viper (left), the pygmy rattlesnake (center) and the mountain garter snake (right) for clues.
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Credit: Western Pygmy Rattlesnake (Sistrurus miliarius streckeri), image by Peter Paplanus from St. Louis, Missouri, Western terrestrial garter snake (Thamnophis elegans terrestris) in San Luis Obispo County, California, by Bill Bouton
Sex-specific chromosomes are a dangerous place to be, if you re a gene. Because these chromosomes Y chromosomes, in humans do not have a matching chromosome with which to exchange genetic information, they are prone to losing non-essential genes left and right in a process called genetic decay. ....

Daniel Winston Bellott , Whitehead Institute Member David Page , Massachusetts Institute Of Technology , Investigator Of The Howard Hughes Medical Institute , Massachusetts Institute , Howard Hughes Medical , Ecology Environment , Zoology Veterinary Science , Sex Linked Conditions , டேனியல் வின்ஸ்டன் பெல்லட் , வைட்ஹெட் நிறுவனம் உறுப்பினர் டேவிட் பக்கம் , மாசசூசெட்ஸ் நிறுவனம் ஆஃப் தொழில்நுட்பம் , புலனாய்வாளர் ஆஃப் தி ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , மாசசூசெட்ஸ் நிறுவனம் , ஹோவர்ட் ஹக்ஸ் மருத்துவ , சூழலியல் சூழல் , ஸுவாலஜீ கால்நடை அறிவியல் , செக்ஸ் இணைக்கப்பட்டுள்ளது நிபந்தனைகள் ,

Geisinger researchers find sex is not an independent risk factor for stroke mortality


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DANVILLE, Pa. - An analysis of data collected from patients treated for ischemic stroke at Geisinger shows no disparity in outcomes based solely on sex.
Various studies have suggested that women are disproportionately affected by stroke and may have poorer stroke outcomes. Women have a longer life expectancy than men and, therefore, likely have an increased lifetime risk of stroke. Women tend to be older than men at the time of stroke and have a higher pre-stroke degree of disability or dependence in their daily activities, which may contribute to worse outcomes. Rural populations may also have a higher risk of stroke based on a greater incidence of conditions like hypertension and poorly controlled diabetes. ....

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