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Researchers develop magnetised nanobeads to detect early-stage cancer


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Researchers develop magnetised nanobeads to detect early-stage cancer
PhD candidate Zennia Jean Gonzaga and Professor Bernd Rehm (Griffith Institute for Drug Discovery), next to the bio-reactor which grows cell factories to make functional polymer particles.
Griffith University researchers have developed a new way to detect cancer biomarkers which could help diagnose early-stage disease.
They bioengineered cell factories to assemble nanobeads with magnetic properties that bind to specific target antibodies. Then the magnetised nanobeads were added to ovarian cancer cells to capture methylated DNA and exosomes (cells) to detect cancer.
“As the nanomaterials can be engineered according to the need for detecting a certain disease type, they are highly flexible and can be tuned for almost any kind of biological molecules that are relevant to detect specific diseases,” Professor Shiddiky said. ....

Bernd Rehm , Zennia Jean Gonzaga , Muhammad Shiddiky , Griffith University , Nanotechnology Centre , Centre For Cell Factories , Applied Materials , Griffith Institute For Drug Discovery , Professor Bernd Rehm , Griffith Institute , Drug Discovery , Associate Professor Muhammad Shiddiky , Queensland Micro , Cell Factories , பர்நெச் ரேஹ்ம் , கிரிஃபித் பல்கலைக்கழகம் , நானோ தொழில்நுட்பம் மையம் , மையம் க்கு செல் தொழிற்சாலைகள் , பயன்படுத்தப்பட்டது பொருட்கள் , கிரிஃபித் நிறுவனம் க்கு மருந்து கண்டுபிடிப்பு , ப்ரொஃபெஸர் பர்நெச் ரேஹ்ம் , கிரிஃபித் நிறுவனம் , மருந்து கண்டுபிடிப்பு , குயின்ஸ்லாந்து மைக்ரோ , செல் தொழிற்சாலைகள் ,

Production of Itaconic Acid in Microorganisms


Production of Itaconic Acid in Microorganisms
Itaconic acid (2-methylidenebutanedioic acid) can be produced by microorganisms and has commercial value as a precursor of polymers, chemicals and fuels. There is interest in using microorganisms to convert biomass into useful products such as itaconic acid. The main itaconic acid producer is the fungal species
Aspergillus terreus, which can produce as much as 86g/L.
Image Credit: Kateryna Kon / Shutterstock.com
What is itaconic acid?
Itaconic acid, also known as 2-methylidenebutanedioic acid, is an unsaturated dicarbonic acid. It is considered to be a value-added product from biomass by the US Department of Energy, as it can be utilized as a precursor of polymers and chemical intermediates. ....

Maho Yokoyama , Kateryna Kon Shutterstock , Us Department Of Energy , Kateryna Kon , Biotechnology Letters , Cell Factories , எங்களுக்கு துறை ஆஃப் ஆற்றல் , உயிரி தொழில்நுட்பவியல் எழுத்துக்கள் , செல் தொழிற்சாலைகள் ,