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Inhibitor Drug Entinostat 'Primes' the Body to Better Respond to Anti-Cancer Treatment with Immunotherapy – India Education | Latest Education News | Global Educational News

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers

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Novel AI Blood Testing Technology Can ID Lung Cancers with High Accuracy

Novel AI Blood Testing Technology Can ID Lung Cancers with High Accuracy
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Researchers develop novel AI blood testing technology to identify lung cancers

Researchers develop novel AI blood testing technology to identify lung cancers
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Paul Reed Smith Music School at Maryland Hall Returns This Week With Legendary Greats | Eye On Annapolis

Paul Reed Smith Music School at Maryland Hall Returns This Week With Legendary Greats | Eye On Annapolis
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Paul Reed Smith Music School at Maryland Hall Returns in August With Legendary Greats | Eye On Annapolis

Paul Reed Smith Music School at Maryland Hall Returns in August With Legendary Greats | Eye On Annapolis
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Paul Reed Smith Music School at Maryland Hall Returns in August With Legendary Greats | Eye On Annapolis

Paul Reed Smith Music School at Maryland Hall Returns in August With Legendary Greats | Eye On Annapolis
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Protein blocks tumor cells spreading via bloodstream

Protein blocks tumor cells spreading via bloodstream
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Specialized protein appears to regulate key step in cancer metastasis


Specialized protein appears to regulate key step in cancer metastasis
Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.
"We have discovered that this protein, TRPM7, senses the pressure of fluid flowing in the circulation and stops the cells from spreading through the vascular system," said Kaustav Bera, a Johns Hopkins University PhD candidate in chemical and biomolecular engineering and a lead author of the study, which was done with colleagues at the University of Alberta and Universitat Pompeu Fabra.
"We found that metastatic tumor cells have markedly reduced levels of this sensor protein, and that is why they efficiently enter into the circulation rather than turning away from fluid flow," said Bera.

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Protein appears to prevent tumor cells from spreading via blood vessels


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VIDEO: In static conditions, cells enter microchannels, whereas 40-60% reverse direction when fluid is flowing. Courtesy of Johns Hopkins University.
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Credit: Johns Hopkins University
Researchers have identified a specialized protein that appears to help prevent tumor cells from entering the bloodstream and spreading to other parts of the body.
"We have discovered that this protein, TRPM7, senses the pressure of fluid flowing in the circulation and stops the cells from spreading through the vascular system," said Kaustav Bera, a Johns Hopkins University PhD candidate in chemical and biomolecular engineering and a lead author of the study, which was done with colleagues at the University of Alberta and Universitat Pompeu Fabra.

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