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Fresh insight into protein production inside brain cells could help tackle Parkinson's


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Wednesday 19 May 2021 - New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.
In a study part-funded by Parkinson s UK, researchers investigated a section of genetic material known as antisense long non-coding RNA (lncRNA), which helps fine-tune the production of the protein tau inside brain cells. This precision in tau regulation is crucial for smooth functioning of the nerve cells.
Understanding the mechanism which helps regulate tau production could be the key to developing better treatments for conditions including Parkinson s, Alzheimer s, corticobasal degeneration and progressive supranuclear palsy. ....

United Kingdom , David Dexter , Roberto Simone , University College London , University Of Trento , Karolinska Institute , Francis Crick Institute , Research At Parkinson United Kingdom , Professor Rohan De Silva , Associate Director , Parkinsons Disease , ஒன்றுபட்டது கிஂக்டம் , டேவிட் டெக்ஸ்டர் , ரொபெர்டோ சிமோன் , பல்கலைக்கழகம் கல்லூரி லண்டன் , பல்கலைக்கழகம் ஆஃப் ட்ரெண்டோ , பிரான்சிஸ் கிரிக் நிறுவனம் , ஆராய்ச்சி இல் பார்கின்சன் ஒன்றுபட்டது கிஂக்டம் , இணை இயக்குனர் ,

New insight into protein production in brain could help tackle dementia


 E-Mail
A pioneering new study led by UCL scientists has revealed, for the first time, a layer of genetic material involved in controlling the production of tau; a protein which plays a critical role in serious degenerative conditions, such as Parkinson s and Alzheimer s disease.
The international research, conducted in mice and cells, also revealed this material is part of a larger family of non-coding genes which control and regulate other similar brain proteins, such as beta-amyloid associated with Alzheimer s and alpha-synuclein implicated in Parkinson s disease and Lewy body dementia.
Researchers say the breakthrough findings, published in
Nature, shed an important new light on how proteins linked to neurological conditions are produced and controlled, and could pave the way for new treatments for a wide range of dementia related diseases. ....

United Kingdom , David Dexter , University Of Trento , Karolinska Institute , Queen Square Institute Of Neurology , United Kingdom Dementia Research Institute , St George University Of London , Research At Parkinson United Kingdom , Research Council , Francis Crick Institute , Reta Lila Weston , Square Institute , Professor Rohan De Silva , Associate Director , Reta Lila Weston Trust , Wellcome Trust , Medical Research Council , Medicine Health , Alzheimers Disease , Parkinsons Disease , ஒன்றுபட்டது கிஂக்டம் , டேவிட் டெக்ஸ்டர் , பல்கலைக்கழகம் ஆஃப் ட்ரெண்டோ , ராணி சதுரம் நிறுவனம் ஆஃப் நரம்பியல் , ஒன்றுபட்டது கிஂக்டம் முதுமை ஆராய்ச்சி நிறுவனம் , ஸ்டம்ப் ஜார்ஜ் பல்கலைக்கழகம் ஆஃப் லண்டன் ,

Seafood company makes big purchase


Seafood company makes big purchase
Updated 7:18 AM;
Ren Seafoods paid $4.17 million for the former Smith’s Bakery building and property at 1201 West I-65 Service Road N. in Mobile, according to Marietta Urquhart and Jamie Ison of White-Spunner Realty, who represented the buyer. David Dexter of CRE Mobile worked for the sellers. Ren Seafoods plans to invest $12.4 million to develop a processing facility and distribution hub. The property includes 15.64 acres with a 70,130-square-foot production area; a cross dock of 35,685 square feet; and a 4,826-square-foot truck service facility. Frios Gourmet Pops leases about 30,000 square feet of the building that was used by the bakery for storage and distribution. ....

United States , Spanish Fort , David Dexter , Brittain Youngblood , Marietta Urquhart , Robert Cook , Vallas Realty , Pinebrook Shopping Center , Jamie Ison Of White Spunner Realty , Ren Seafoods , Jamie Ison , White Spunner Realty , Gourmet Pops , New Orleans , Youngblood Real Estate , ஒன்றுபட்டது மாநிலங்களில் , ஸ்பானிஷ் கோட்டை , டேவிட் டெக்ஸ்டர் , மரியெட்டா அர்கோவார்ட் , ராபர்ட் சமைக்கவும் , வல்லாஸ் ரியல்டீ , ரென் கடல் உணவுகள் , குர்‌மை பாப்ஸ் , புதியது ஆர்லீயந்ஸ் ,