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Anti-inflammatory nanoparticles could be applied to the weakening muscles of DMD patients


Anti-inflammatory nanoparticles could be applied to the weakening muscles of DMD patients
Muscular dystrophies are a group of genetic diseases that lead to the progressive loss of muscle mass and function in patients, with the incurable Duchenne Muscular Dystrophy (DMD), which affects all the body s muscles primarily in boys, being particularly severe.
DMD can be caused by more than 7,000 unique mutations in the largest gene of the human genome, which encodes a central protein in muscle fibers. While this astounding number of mutations all variably block muscle function, the affected muscles share another common feature - chronic inflammation.
As chronic inflammation significantly contributes to the speed and severity of muscle degeneration, researchers are pursuing different anti-inflammatory approaches that could be applied to the weakening muscles of DMD patients. ....

David Mooney , Theresa Raimondo , Robertp Pinkas , Emily Henderson , Harvard Wyss Institute For Biologically Inspired Engineering , Johna Paulson School Of Engineering , Wyss Institute Founding Core Faculty , Wyss Institute Immuno , Duchenne Muscular Dystrophy , Wyss Institute , Biologically Inspired Engineering , Applied Sciences , Immuno Materials Platform , Family Professor , Postdoctoral Fellow , டேவிட் மூனி , எமிலி ஹென்டர்சன் , ஜொன்னா பால்சன் பள்ளி ஆஃப் பொறியியல் , விஸ் நிறுவனம் ஸ்தாபகம் கோர் ஆசிரிய , விஸ் நிறுவனம் இம்யூனோ , விஸ் நிறுவனம் , பயன்படுத்தப்பட்டது அறிவியல் , குடும்பம் ப்ரொஃபெஸர் , போஸ்ட்‌டாக்டொரல் சக ,