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cRNA circ_0003221 promotes cervical cancer progression

14 have been identified to promote cervical cancer progression, suggesting the important role of circRNAs in cervical cancer tumorigenesis. As for circ 0003221 (also known as circPTK2, chr8:141856358–141900868), it has been demonstrated to be overexpressed in cervical cancer cells.
15 Nevertheless, the role of circ 0003221 in cervical cancer remains largely unclear.
Large evidence has shown that circRNAs can serve as competing endogenous RNAs (ceRNAs), also known as microRNA (miRNA) sponges, via competitively binding to miRNA response elements, thereby regulating the expression of downstream target genes.
16,17 Based on this regulation, circRNAs can function as miRNA sponges to regulate the expression of target genes, forming a regulatory circRNA-miRNA-mRNA network. MiR-758 has been identified to serve as a tumor-suppressing miRNA in cervical cancer. ....

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Bharat Biotech Concludes Final Analysis for COVAXIN® Efficacy from Phase 3 Clinical Trials

Bharat Biotech Concludes Final Analysis for COVAXIN® Efficacy from Phase 3 Clinical Trials
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COVAXIN demonstrates overall efficacy of 77.8% in ph 3 clinical trial

COVAXIN demonstrates overall efficacy of 77.8% in ph 3 clinical trial
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New study shows how our brains sync hearing with vision -- Science of the Spirit -- Sott.net

Tue, 11 May 2021 18:32 UTC
To make sense of complex environments, brain waves constantly adapt, compensating for drastically different sound and vision processing speeds
© Montreal Neurological Institute-Hospital
MEG signals revealed that recalibration was enabled by a unique interaction between fast and slow brain waves in auditory and visual brain regions.Every high-school physics student learns that sound and light travel at very different speeds. If the brain did not account for this difference, it would be much harder for us to tell where sounds came from, and how they are related to what we see.
Instead, the brain allows us to make better sense of our world by playing tricks, so that a visual and a sound created at the same time are perceived as synchronous, even though they reach the brain and are processed by neural circuits at different speeds. ....

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Depletion of Circular RNA circ_CORO1C Suppresses Gastric Cancer Develo

Depletion of Circular RNA circ CORO1C Suppresses Gastric Cancer Development by Modulating miR-138-5p/KLF12 Axis ....

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