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Scientists discover cellular stress enzyme that might play key role in neurodegenerative diseases such as ALS

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An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress response is a possible cause of injury to brain cells in neurodegenerative diseases such as Alzheimer s, Parkinson s, and Amyotrophic Lateral Sclerosis. The discovery will make MARK2 a focus of investigation for its possible role in these diseases, and may ultimately be a target for neurodegenerative disease treatments.
In addition to its potential relevance to neurodegenerative diseases, the finding is an advance in understanding basic cell biology. ....

Xumei Zhang , Jiou Wang , Dao Nguyen , Sarah Kavianpour , Tao Zhang , Ravi Thombre , Bloomberg School , Johns Hopkins Bloomberg School Of Public Health , Department Of Biochemistry , Johns Hopkins Bloomberg School , Amyotrophic Lateral , Molecular Biology , Medicine Health , Alzheimers Disease , Parkinsons Disease , Public Health , டாவோ ஂக்யந் , தாவோ ஜாங் , ரவி தொம்ப்ரே , ப்ளூம்பெர்க் பள்ளி , ஜான்ஸ் ஹாப்கின்ஸ் ப்ளூம்பெர்க் பள்ளி ஆஃப் பொது ஆரோக்கியம் , துறை ஆஃப் உயிர் வேதியியல் , ஜான்ஸ் ஹாப்கின்ஸ் ப்ளூம்பெர்க் பள்ளி , மூலக்கூறு உயிரியல் , மருந்து ஆரோக்கியம் , அல்சைமர் நோய் ,

Scientists move closer to developing 'game-changing' test to diagnose Parkinson's

Results published today show it is possible to identify Parkinson s based on compounds found on the surface of skin. The findings offer hope that a pioneering new test could be developed to diagnose the degenerative condition through a simple and painless skin swab. ....

United Kingdom , City Of , Perdita Barran , David Dexter , Tilo Kunath , Daxa Kalayci , Nature Communications , University Of Manchester Innovation Factory , Professor Monty Silverdale At Salford Royal Foundation , Michaelj Fox Foundation , University Of Manchester , Research At Parkinson United Kingdom , University Of Edinburgh , Manchester Innovation , Joy Milne , Professor Perdita Barran , Professor Monty Silverdale , Salford Royal Foundation Trust , Manchester Innovation Factory , Mass Spectrometry , Associate Director , Cell Biology , Medicine Health , Parkinsons Disease , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் ,

Revealing the Many Faces of COVID-19

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CDC s Deblina Datta (r.) hosted her mother Chitra Datta early in the pandemic. Chitra lives in New York, and when COVID-19 first broke out there, she took refuge at her daughter s Atlanta home, where Deblina teleworked, leading a clinical team on CDC s COVID-19 emergency response.
People can survive a COVID-19 infection in the lungs only to come down with new symptoms in other parts of the body. This is yet another way that COVID-19 is a particularly bad viral disease, says Deblina Datta, a CDC doctor who researches how infectious diseases make people sick.
Deblina has spent more than nine months on CDC’s COVID-19 emergency response, mostly leading a team of more than 40 clinicians concentrating on healthcare and protecting workers during the pandemic. She has spent decades trying to stop the spread of viral diseases like AIDS and hepatitis. But during her time on the response, she found the virus that causes COVID-19 to cause more ailments than nea ....

New York , United States , Chitra Datta , Deblina Datta , Us Public Health Serviceexternal , Health Serviceexternal , New York City , Covid 19 , Long Covid , Heart Failure , Sars Cov 2 , Coronavirus Cov , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , சித்ரா தத்தா , டெப்லினா தத்தா , புதியது யார்க் நகரம் , இதயம் தோல்வி ,

Lifestyle research studies to reduce risk of Alzheimer's respond to COVID-19 challenges

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The impact of the COVID-19 pandemic on public health is staggering; more than one hundred million cases and two million deaths worldwide. In response, most countries and local governments have taken substantial measures such as travel restrictions and physical distancing to keep their citizens safe. Both the pandemic and related protective measures pose challenges for ongoing clinical research studies seeking to treat and prevent the world s greatest public health emergencies including COVID-19, but also Alzheimer s disease and other dementia.
In a new paper from the World-Wide FINGERS network in Alzheimer s & Dementia: Translational Research and Clinical Interventions, first author Susanne Röhr, Ph.D., clinical psychologist at the Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Germany, and colleagues provide timely guidance on the design and management of clinical research during COVID-19 specifically on the co ....

Hidenori Arai , Mark Espeland , Mariac Carrillo , Miia Kivipelto , National Center , Global Brain Health Institute , Occupational Health , Institute Of Social Medicine , Brain Health , Clinical Geriatrics At Karolinska Institute , Public Health , University Of Leipzig , Alzheimer Association , Translational Research , Medicine At Wake Forest School Of , Translational Research Clinical Interventions , Clinical Interventions , Social Medicine , Atlantic Fellow , Global Brain Health , Internal Medicine , Wake Forest School , Clinical Geriatrics , Karolinska Institute , Analysis Plans , Multidomain Intervention Clinical Trials ,

Welcome To IANS Live - SCIENCE - Qualcomm working on next-gen Snapdragon chipset

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New Delhi, March 11 (IANS) Qualcomm is working on the next-generation Snapdragon 8cx chipset, with an aim to take on the likes of Apple Silicon M1 chip.
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Update: 11-March-2021 ....

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