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Auditory brainstem pathways do not develop properly without microglia

Auditory pathways in the brainstem do not fully mature without microglia clearing away extra cell connections. This crucial function occurs even when pruning by microglia is delayed, according to new research published in eNeuro. ....

Society For Neuroscience , Inhibitor Largely Recover With Microglial , Medicine Health , Hearing Speech , Parenting Child Care Family , சமூகம் க்கு நரம்பியல் , மருந்து ஆரோக்கியம் , கேட்டல் பேச்சு , பெற்றோருக்குரியது குழந்தை பராமரிப்பு குடும்பம் ,

Can the brain resist the group opinion?

Credit: HSE University
Scientists at HSE University have learned that disagreeing with the opinion of other people leaves a trace in brain activity, which allows the brain to later adjust its opinion in favour of the majority-held point of view. The article was published in
Scientific Reports.
We often change our beliefs under the influence of others. This social behavior is called conformity and explains varios components of our behaviour, from voting at elections to fashion trends among teenagers.
Brain research has recently well informed about short-term effects of social influence on decision making. If our choice coincides with the point of view of the people who are important to us, this decision is reinforced in the brain s pleasure centres involved in the larger dopaminergic system responsible for learning, motor activity and many other functions. Conversely, in instances of disagreement with others, the brain signals that a mistake has been made ....

City Of , United Kingdom , Aleksei Gorin , University Professor Vasily Klucharev , Professor Vasily Klucharev , Social Behavioral Science , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , சமூக நடத்தை அறிவியல் ,

Correspondence between representations in visual cortices and neural networks

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IMAGE: The study reported the similar properties between deep neural networks for predicting attention and the primary visual cortex (V1) of primates.
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Credit: Nobuhiko Wagatsuma
This discovery was made possible by applying the research method for the comparison of the brain activity between monkeys and humans to artificial neural networks. This finding might be helpful not only to understand the cortical mechanism of attentional selection but also to develop artificial intelligence.
Deep neural networks (DNNs), which are used in the development of artificial intelligence, are mathematical models for obtaining appropriate mechanisms to solve specific problems from the training with a large-scale dataset. However, the detailed mechanisms underlying DNNs through this learning process have not yet been clarified. ....

United States , Hiroshi Tamura , Akinori Hidaka , Nobuhiko Wagatsuma , School Of Frontiers Biosciences , Society For Neuroscience Sf , Osaka University , Tokyo Denki University , Toho University , Associate Professor , Graduate School , Frontiers Biosciences , ஒன்றுபட்டது மாநிலங்களில் , ஹிரோஷி தமுரா , பள்ளி ஆஃப் எல்லைகள் உயிர் அறிவியல் , சமூகம் க்கு நரம்பியல் எஸ் எப் , ஒசகக பல்கலைக்கழகம் , தோஹோ பல்கலைக்கழகம் , இணை ப்ரொஃபெஸர் , பட்டதாரி பள்ளி , எல்லைகள் உயிர் அறிவியல் ,

Molecular sleuthing identifies and corrects major flaws in blood-brain barrier model

A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center. ....

Tyler Lu , Ronaldo Perelman , David Redmond , Columbia University Irving Medical Center , Claudia Cohen Center , Proceedings Of The National Academy Sciences , Ansary Stem Cell Institute , Memorial Sloan Kettering Cancer Center , Weill Cornell Medicine , Columbia University Irving Medical , Brain Microvascular Endothelial Cell , National Academy , Regenerative Medicine , Weill Cornell , Reproductive Medicine , Medicine Health , டைலர் லு , ரொனள்டோ பெரல்மேன் , டேவிட் ரெட்மண்ட் , கொலம்பியா பல்கலைக்கழகம் இவிஂக் மருத்துவ மையம் , கிளாடியா கோஹன் மையம் , பதில் தண்டு செல் நிறுவனம் , நினைவகம் ஸ்லோன் கெட்டரிங் புற்றுநோய் மையம் , வெயில் கார்னெல் மருந்து , கொலம்பியா பல்கலைக்கழகம் இவிஂக் மருத்துவ , தேசிய கலைக்கழகம் ,

Brain protein that causes Alzheimer's also protects against the disease: USask research

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IMAGE: Molecular neurochemist Darrell Mousseau is a professor in USask s Department of Psychiatry and head of the Cell Signalling Laboratory.
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Credit: University of Saskatchewan
Findings from a new study on Alzheimer s disease (AD), led by researchers at the University of Saskatchewan (USask), could eventually help clinicians identify people at highest risk for developing the irreversible, progressive brain disorder and pave the way for treatments that slow or prevent its onset.
The research, published in the journal
Scientific Reports in early January, has demonstrated that a shorter form of the protein peptide believed responsible for causing AD (beta-amyloid 42, or Aβ42) halts the damage-causing mechanism of its longer counterpart. ....

Carlos Carvalho , Joseph Buttigieg , Jason Maley , Darrell Mousseau , Scot Leary , Maa Quartey , Jennifer Nyarko , Cell Signalling Laboratory , University Of Saskatchewan Usask , Alzheimer Society Of Saskatchewan , Matt Parsons At Memorial University Of Newfoundland , Department Of Biochemistry , Saskatchewan Health Research Foundation , Saskatchewan Structural Sciences Centre , Department Of Biology , Usask Department Of Psychiatry , Cell Signalling Lab Department Of Psychiatry , University Of Regina , Saskatchewan Research , Scientific Reports , Cell Signalling , Saskatchewan Research Chair , Alzheimer Society , Cell Signalling Lab , Matt Parsons , Memorial University ,