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Synthetic biology circuits can respond within seconds


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Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.
 
However, there is often a long lag time between an event such as detecting a molecule and the resulting output, because of the time required for cells to transcribe and translate the necessary genes. MIT synthetic biologists have now developed an alternative approach to designing such circuits, which relies exclusively on fast, reversible protein-protein interactions. This means that there’s no waiting for genes to be transcribed or translated into proteins, so circuits can be turned on much faster within seconds. ....

Bonnie Berger , Brian Teague , Ron Weiss , Tristan Bepler , Deepak Mishra , National Science Foundation Graduate Research Fellowship Program , Artificial Intelligence Laboratory , Department Of Biological Engineering , Institute For Collaborative Biotechnologies , National Institutes Of Health , National Science Foundation , Department Of Biochemistry , University Of Wisconsin , Us Army Research Office , Energy Research Fellowship , Biological Engineering , Simons Professor , Jim Broach , Molecular Biology , Penn State Hershey Medical , Siebel Scholars Award , Research Fellowship , Collaborative Biotechnologies , Research Office , Integrated Synthetic Biology , National Institutes ,

UCSB's Rachel Segalman, Craig Hawker Elected to National Academy of Engineering | UCSB


Craig Hawker
Two UC Santa Barbara engineers are among 129 new members worldwide elected to the National Academy of Engineering (NAE) for 2021. Materials and chemistry professor Craig Hawker and Rachel Segalman, chair of the Chemical Engineering Department, join the 106 American and 23 foreign engineers honored this year.
Election to the NAE is among the highest professional distinctions accorded to an engineer.
Segalman, the Edward Noble Kramer Professor and a professor of both chemical engineering and materials, was recognized “for contributions to semiconducting block polymers, polymeric ionic liquids and hybrid thermoelectric materials.”
Hawker, the Alan and Ruth Heeger Chair in Interdisciplinary Science, who also serves as the director of the California NanoSystems Institute (CNSI) and the Dow Materials Institute, was cited for ”contributions to polymer chemistry through synthetic organic chemistry concepts and the advancement of molecular engineering pr ....

United States , United Kingdom , Henryt Yang , Craig Hawker , Ruth Heeger , Rachel Segalman , Santa Barbara , Ted Kramer , Royal Society , Institute For Collaborative Biotechnologies , University Of Queensland , Materials Research Laboratory , National Science Foundation Early , University Of Cambridge , National Academy Of Engineering , American Physical Society , Energy Systems , College Of Engineering , American Academy Of Arts , Mitsubishi Chemical Center , Cornell University , Dow Materials Institute , University Of Texas At Austin , Chemical Engineering Department , National Academy Of Inventors , California Nanosystems Institute ,