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A tummy invader: This bacterial molecule may be key to fighting stomach cancer

Researchers from Osaka University found that ....

Ryo Kinoshita Daitoku , Hitomi Mimuro , Nature Communications , Osaka University , Medicine Health , இயற்கை தகவல்தொடர்புகள் , ஒசகக பல்கலைக்கழகம் , மருந்து ஆரோக்கியம் ,

Researchers engineer probiotic yeast to produce beta-carotene

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Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.
There are clear advantages to being able to engineer probiotics so that they produce the desired molecules right where they are needed, says Nathan Crook, corresponding author of the study and an assistant professor of chemical and biomolecular engineering at North Carolina State University. You re not just delivering drugs or nutrients; you are effectively manufacturing the drugs or nutrients on site. ....

Abdulkerim Eroglu , Ibrahim Alabri , Junrui Cheng , Deniz Durmusoglu , Scott Collins , National Science Foundation , Helmholtz Institute , Infection Research , Plants For Human Health Institute , Department Of Molecular , Nc State University , Novo Nordisk Foundation , Carolina State University , Nathan Crook , North Carolina State , Ibrahim Al Abri , Structural Biochemistry , Human Health Institute , Chase Beisel , Technology Engineering Computer Science , Biomedical Environmental Chemical Engineering , ஸ்காட் கோலின்ஸ் , தேசிய அறிவியல் அடித்தளம் , தொற்று ஆராய்ச்சி , செடிகள் க்கு மனிதன் ஆரோக்கியம் நிறுவனம் , துறை ஆஃப் மூலக்கூறு ,

Pain receptors linked to the generation of energy-burning brown fat cells

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BOSTON - (April 12, 2021) - A new source of energy expending brown fat cells has been uncovered by researchers at the Joslin Diabetes Center, which they say points towards potential new therapeutic options for obesity. According to the new report, published today by
Nature Metabolism, the key lies in the expression of a receptor called Trpv1 (temperature-sensitive ion channel transient receptor potential cation subfamily V member 1) a protein known to sense noxious stimuli, including pain and temperature.
Specifically, the authors point to smooth muscle cells expressing the Trpv1 receptor and identify them as a novel source of energy-burning brown fat cells (adipocytes). This should translate into increased overall energy expenditure - and ultimately, researchers hope, reduced weight. ....

United States , United Kingdom , Yu Hua Tseng , Anushka Gupta , Matthewd Lynes , University Of California , National Institute Of Diabetes , Joslin Diabetes Center , Tian Lian Huang Joslin Diabetes Center , American Diabetes Association , Us National Institutes Of Health , Li Lun Ho Massachusetts Institute Of Technology , Nature Metabolism , Mary Piper , Public Health , Massachusetts Institute , Tian Lian Huang , Aaron Streets , National Institute , Kidney Diseases , American Diabetes , Cell Biology , Molecular Biology , Eating Disorders Obesity , Metabolism Metabolic Diseases , ஒன்றுபட்டது மாநிலங்களில் ,

The 17th-century cloth merchant who discovered the vast realm of tiny microbes – an appreciation of Antonie van Leeuwenhoek

Leeuwenhoek, who discovered bacteria, is one of the most important figures in the history of medicine, laying the groundwork for today's understanding of infectious disease. ....

City Of , United Kingdom , Robert Hooke , H Cook Jr , J Verolje Wellcome , Royal Society , Associated Press , Wellcome Collection , Thomas Splettstoesser , History Of Medicine , History Of Science , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , ராபர்ட் கொக்கி , ஏச் சமைக்கவும் ஜூனியர் , அரச சமூகம் , தொடர்புடையது ப்ரெஸ் , வெல்கம் சேகரிப்பு , வரலாறு ஆஃப் மருந்து , வரலாறு ஆஃப் அறிவியல் ,

James Mcallister was a much-loved family man. Did the Christmas mixing confusion cause his death?

James Mcallister was a much-loved family man. Did the Christmas mixing confusion cause his death?
James Mcallister … ‘I thought that if James got Covid, he would be really poorly or it would kill him.’ Illustration: PAUL RYDING/The Guardian
James Mcallister … ‘I thought that if James got Covid, he would be really poorly or it would kill him.’ Illustration: PAUL RYDING/The Guardian
In the run-up to Christmas, the government dithered and made last-minute rule changes that left many people baffled. A surge in coronavirus cases soon followed
Tue 6 Apr 2021 01.00 EDT
All through the spring of 2020, and into the summer, Michelle Mcallister carefully shielded her husband, James Mcallister. Michelle, 39, who lives in the Wednesfield area of Wolverhampton, was a full-time carer to James, 52. A former used car dealer, James had heart failure and had used a colostomy bag since a stomach ulcer burst in 2016. He was unable to work and was often in pain, reliant ....

Saudi Arabia , United Kingdom , City Of , Jo Goodman , Andrew Hayward , Devi Sridhar , James Mcallister , Michelle Mcallister , Stephen Reicher , Boris Johnson , University Of Southampton , Scientific Advisory Group For Emergencies Sage , Fudan University , University Of Edinburgh , University Of St Andrews , Christmas Day , Scientific Advisory Group , Prof Andrew Hayward , Prof Stephen Reicher , Independent Sage , Prof Devi Sridhar , Corona Virus , Infectious Diseases , Medical Research , World News , சவுதி அரேபியா ,