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Frontiers | Insights Into Excess Mortality During the First Months of the COVID-19 Pandemic From a Rural, Demographic Surveillance Site in Bangladesh


Health Systems and Population Studies Division, icddr, b, Dhaka, Bangladesh
Background: Coronavirus disease 2019 (COVID-19) has spread globally, and the government of each affected country is publishing the number of deaths every day. This official figure is an underestimate as it excludes anybody who did not die in a hospital, who did not test positive, who had a false result, or those who recovered on their own without a test.
Objective: This study aimed to measure the community level excess mortality using health and demographic surveillance in a rural area of Bangladesh.
Method: The study was conducted in Matlab, in a rural area of Bangladesh, with a Health and Demographic Surveillance System (HDSS) covering a population of 239,030 individuals living in 54,823 households in 142 villages. We examined the mortality in January-April from 2015 to 2020 and compared the mortality in 2020 with the historical trend of 2015–2019. Between 2015 and 2020, we followed 276,868 ....

United Kingdom , South Korea , New York , United States , South Africa , Saudi Arabia , Eastern Cape , Zahirul Haq , Sahara Africa , Rahmant Covid , Ethical Review Committee , Bangladesh Suspends All International Flights , World Health Organization , Registration Of Health , Health Sector Resource Mobilisation , World Health Organisation , Public Health , New York Times , Vital Statistics Benefit Health , Front Public Health , Sankoho Health , Global Health , National Institute , Huanan Seafood Wholesale Market , Demographic Surveillance System , Coronavirus Disease ,

Pregnancy Following Diagnosis of Adrenoleukodystrophy


Background: Adrenoleukodystrophy (ALD) is a rare sex-linked recessive disorder that disrupts adrenal gland function and the white matter of the nervous system. According to recent epidemiological statistics, up to this moment, the disease is the most recorded peroxisomal disorder.
ABCD1 is a gene related to ALD, with more than 850 unique mutations have been reported. Early diagnosis of the disease would help to consult families with ALD to plan for interventions to prevent passing along the pathogenic mutations to their children.
Material and Methods: A heterozygous
ABCD1 gene mutation related to ALD found in a Vietnamese woman was used to design primers for the polymerase chain reaction (PCR) to amplify the segment spanning the mutation. Then, combining sequencing methods for the PCR products, especially Sanger sequencing and next-generation sequencing (NGS), a protocol was developed to detect mutations on the ....

Republic Of , Eteläuomen Läi , Miriam Iglesias , Spectramax Quickdrop , European Society For Human Reproduction , Preimplantation Genetic Diagnosis Program , Institute Of Clinical Embryology , European Society , Human Reproduction , Next Generation Sequencing , Ethical Review Committee , Vietnam Military Medical University , Military Institute , Clinical Embryology , Genome Amplification , Single Cell Kit , Chain Reaction , Wide Midi Horizontal Electrophoresis System , Cleaver Scientific , Genetic Diagnosis Program , Fertilization Embryos , Annotating Sanger Sequencing , குடியரசு ஆஃப் , மிரியம் இக்லேஸியேஸ் , ஐரோப்பிய சமூகம் க்கு மனிதன் இனப்பெருக்கம் , ஐரோப்பிய சமூகம் ,