Page 8 - நொதி தொழில்நுட்பங்கள் நிறுவனம் News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Stay updated with breaking news from நொதி தொழில்நுட்பங்கள் நிறுவனம். Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Top News In நொதி தொழில்நுட்பங்கள் நிறுவனம் Today - Breaking & Trending Today

Novel method can improve the detection of circulating tumor cells


Novel method can improve the detection of circulating tumor cells
Non-Small Cell Lung Cancer (NSCLC) is the most prevalent form of lung cancer, accounting for more than 80 percent of all lung cancer cases. Despite the aggressive nature of NSCLC, circulating tumor cells that lead to metastases often go undetected in the blood compared to breast, prostate, colorectal, and other cancers.
Now, scientists have developed a novel method to better detect the circulating tumor cells (CTCs) that are a telltale sign of metastases. The research was published in the journal
Proceedings of the National Academy of Sciences (
PNAS).
ISB and a collaborative team of researchers looked at hexokinase-2, or HK2, a key enzyme in glucose metabolism. A set of previous reports from our collaborator Dr. Herschman (co-author of the paper) and others revealed that cancer cells often rely on HK2 to elevate glucose metabolism to fuel their uncontrolled growth, making this enzyme a desirab ....

Emily Henderson , Proceedings Of The National Academy Sciences , Institute For Systems Biology , Small Cell Lung Cancer , National Academy , Study Lead Corresponding Author , Lung Cancer , Non Small Cell Lung Cancer , Glucose Metabolism , எமிலி ஹென்டர்சன் , நிறுவனம் க்கு அமைப்புகள் உயிரியல் , சிறிய செல் நுரையீரல் புற்றுநோய் , தேசிய கலைக்கழகம் , நுரையீரல் புற்றுநோய் , அல்லாத சிறிய செல் நுரையீரல் புற்றுநோய் , வளர்சிதை மாற்றம் ,

Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins


Researchers identify human BCAS3 and C16orf70 as novel autophagic proteins
Autophagy is an intracellular degradation process of cytosolic materials and damaged organelles. Researchers at Ubiquitin Project of TMIMS have been studying the molecular mechanism of mitophagy, the selective autophagy process to eliminate damaged mitochondria. PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria, then ubiquitin chains are recognized as signals for autophagy degradation. Dysfunction of mitophagy causes a decrease in mitochondrial quality with overproduction of ROS, and is linked to neurodegenerative diseases like Parkinson s disease. ....

Emily Henderson , Ubiquitin Project , Breast Carcinoma Amplified Sequence , Drug Discovery , Life Science , Neurodegenerative Diseases , Parkinson 39s Disease , எமிலி ஹென்டர்சன் , மார்பக புற்றுநோய் பெருக்கப்பட்டது வரிசை , மருந்து கண்டுபிடிப்பு , வாழ்க்கை அறிவியல் ,