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Similar factors cause health disparities in cancer, COVID-19

Credit: Michigan Medicine
ANN ARBOR, Michigan Income level, employment, housing location, medical insurance, education, tobacco and alcohol use, diet and obesity, access to medical care. These are some of the factors causing worse cancer outcomes in people who are Black.
The same factors are also causing worse outcomes from COVID-19 in this population.
The similarities between COVID-19 issues and cancer disparities is uncanny, says John M. Carethers, M.D., John G. Searle Professor and Chair of Internal Medicine at Michigan Medicine.
In cancer we are seeing in slow motion what has been observed rapidly with COVID - that the same conditions in our society put specific groups at risk for both. If we can fundamentally change socioeconomic inequality, we theoretically could reduce disparities in both diseases, says Carethers, who is a member of the University of Michigan Rogel Cancer Center. ....

United States , Johng Searle , Roberta Winn , Lisaa Newman , Johnm Carethers , Michigan Health Lab , University Of Michigan Rogel Cancer Center , Virginia Commonwealth University , Clinical Cancer Research , Internal Medicine , Michigan Rogel Cancer , Weill Cornell Medicine , Michigan Rogel Cancer Center , Health Lab , Medicine Cancer Answerline , ஒன்றுபட்டது மாநிலங்களில் , ரோபர்ட்டா வென்றது , லிசா புதியவர் , மிச்சிகன் ஆரோக்கியம் ஆய்வகம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , வர்ஜீனியா காமன்வெல்த் பல்கலைக்கழகம் , மருத்துவ புற்றுநோய் ஆராய்ச்சி , உள் மருந்து , மிச்சிகன் ரோஜல் புற்றுநோய் , வெயில் கார்னெல் மருந்து , மிச்சிகன் ரோஜல் புற்றுநோய் மையம் ,

Prostate cancer regulator plays role in COVID-19, providing a promising treatment lead

Prostate cancer regulator plays role in COVID-19, providing a promising treatment lead
ANN ARBOR, Michigan By taking a lesson from prostate cancer, researchers now have a promising lead on a treatment for COVID-19.
Two proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, M.D., Ph.D. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers. They also knew that TMPRSS2 was regulated by the androgen receptor.
So when cancer research shut down in the spring, Chinnaiyan s lab turned its attention to the coronavirus. With a grant from the National Cancer Institute, the team used its existing knowledge and resources to determine how TMPRSS2 was regulated in the lungs. ....

Michigan Center , United States , Gregory Raskind , Jonathanz Sexton , Stephaniea Simko , Jessew Wotring , Jean Ching Yi Tien , Sylvia Zelenka Wang , Steven Kregel , Sathiyap Narayanan , Pushpinder Bawa , Ingridj Apel , Xuhong Cao , Abhijit Parolia , Fengyun Su , Lanbo Xiao , Rohit Mehra , Danr Robinson , Xiaoming Wang , Yuanyuan Qiao , Stephaniej Ellison , Rahul Mannan , Arul Chinnaiyan , Yuping Zhang , Lisa Mcmurry , Sethuramasundaram Pitchiaya ,

Concern about loved ones might motivate people to mask up and get vaccine

Concern about loved ones might motivate people to mask up and get vaccine
ANN ARBOR, Michigan While many people have listened to messaging about wearing a mask and following social distancing guidelines to limit the spread of COVID-19, resistance remains. A new study finds that appealing to people s concerns for their loved ones could overcome this resistance. And it may have implications for encouraging people to get the new vaccine.
In a recent survey, people who said social distancing and COVID-safety guidelines violated their personal freedoms responded more positively to these ideas when they felt a loved one might be at risk of severe illness for COVID-19. ....

United States , Sarah Hawley , M Lee Van Horn , Kenneth Resnicow , Health Communications Research , National Cancer Institute , University Of Michigan Rogel Cancer Center , Rogel Cancer Center , Um School Of Public Health , Michigan Medicine , Michigan Rogel Cancer Center , Health Communications , Um School , Public Health , Rogel Cancer , Van Horn , Elizabeth Bacon , Google Focus , Patient Education , Keeping Loved Ones Safe , ஒன்றுபட்டது மாநிலங்களில் , சாரா ஹவ்லி , மீ லீ வேன் கொம்பு , ஆரோக்கியம் தகவல்தொடர்புகள் ஆராய்ச்சி , தேசிய புற்றுநோய் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் ,

Landmark study finds how often cancer patients develop osteonecrosis of the jaw

Landmark study finds how often cancer patients develop osteonecrosis of the jaw
A landmark study by researchers from the SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), has found that 2.8 percent of patients on average develop osteonecrosis of the jaw, or ONJ, within three years of starting a common treatment for cancer that has spread to the bone.
Appearing in
JAMA Oncology, the findings are important because the treatment, zoledronic acid, is prescribed to tens of thousands of patients whose cancer has spread to the bone. Almost all forms of cancer can spread, or metastasize, to bone but the most common are lung, breast, and prostate cancers and multiple myeloma. Zoledronic acid can protect bone, but is associated with a risk of ONJ, which causes exposed bone in the jaw that does not heal. This causes inflammation and pain in the mouth, and people with ONJ ma ....

Catherine Van Poznak , Van Poznak , Emily Henderson , National Clinical Trials Network , National Cancer Institute , Community Oncology Research Program , National Institutes Of Health , Cancer Research Network , University Of Michigan Rogel Cancer Center , Research Network , National Institutes , Clinical Trials Network , Oncology Research , Michigan Rogel Cancer Center , கேத்தரின் வேன் போஜ்னக் , வேன் போஜ்னக் , எமிலி ஹென்டர்சன் , தேசிய மருத்துவ சோதனைகள் வலைப்பின்னல் , தேசிய புற்றுநோய் நிறுவனம் , சமூக புற்றுநோயியல் ஆராய்ச்சி ப்ரோக்ர்யாம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , புற்றுநோய் ஆராய்ச்சி வலைப்பின்னல் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , ஆராய்ச்சி வலைப்பின்னல் , தேசிய நிறுவனங்கள் , மருத்துவ சோதனைகள் வலைப்பின்னல் ,

Concern about loved ones might motivate people to mask up and get vaccine

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ANN ARBOR, Michigan While many people have listened to messaging about wearing a mask and following social distancing guidelines to limit the spread of COVID-19, resistance remains. A new study finds that appealing to people s concerns for their loved ones could overcome this resistance. And it may have implications for encouraging people to get the new vaccine.
In a recent survey, people who said social distancing and COVID-safety guidelines violated their personal freedoms responded more positively to these ideas when they felt a loved one might be at risk of severe illness for COVID-19.
Emphasizing the benefits of being a protector for others (instead of yourself) looks to be more effective in promoting greater adherence to recommended practices, says study author Lawrence An, M.D., associate professor of general medicine at Michigan Medicine and co-director of the University of Michigan Rogel Cancer Center s Center for Health Communications Research. ....

United States , Sarah Hawley , M Lee Van Horn , Kenneth Resnicow , Health Communications Research , National Cancer Institute , University Of Michigan Rogel Cancer Center , Rogel Cancer Center , Um School Of Public Health , Michigan Medicine , Michigan Rogel Cancer Center , Health Communications , Um School , Public Health , Rogel Cancer , Van Horn , Elizabeth Bacon , Google Focus , Patient Education , Keeping Loved Ones Safe , ஒன்றுபட்டது மாநிலங்களில் , சாரா ஹவ்லி , மீ லீ வேன் கொம்பு , ஆரோக்கியம் தகவல்தொடர்புகள் ஆராய்ச்சி , தேசிய புற்றுநோய் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் ,