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Immune therapy after surgery lowers relapse risk in patients with high-risk melanoma


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IMAGE: Kenneth Grossmann, MD, PhD, of Huntsman Cancer Institute, led the SWOG S1404 clinical trial, which found that patients with high-risk melanoma who had pembrolizumab after their surgery had a longer.
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Credit: Huntsman Cancer Institute
PORTLAND, OR - Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery. These findings of a large SWOG Cancer Research Network clinical trial, S1404, will be presented at the ASCO annual meeting June 6, 2021.
Researchers also measured overall survival and found no statistically significant difference in overall survival rates between the two groups of patients three and one-half years after the last patient enrolled to the trial. They did find, however, that patients taking pembrolizumab had fewer serious side effects than those treated with e ....

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SWOG researchers to present practice-changing research at virtual ASCO 2021


SWOG researchers to present practice-changing research at virtual ASCO 2021
SWOG always brings an impressive portfolio of work to the ASCO annual meeting, said SWOG Chair Charles D. Blanke, MD, and this year I m particularly excited about the research our investigators are presenting because it includes results that are likely to be practice-changing.
Investigators will present 12 abstracts from SWOG-led or co-led studies and 11 abstracts from studies led by other groups within the National Clinical Trials Network (NCTN).
Results from S1216 will be presented orally by study chair Neeraj Agarwal, MD, of the Huntsman Cancer Institute at the University of Utah. S1216 compared androgen deprivation therapy (ADT) combined with TAK-700 to the standard treatment of ADT with bicalutamide in patients who had metastatic hormone-sensitive prostate cancer. The study found that adding TAK-700 to ADT lengthened median progression-free survival in these patients and improved prost ....

United States , United Kingdom , University Of California Davis , Roche Genentech , Peter Black , Davendra Sohal , Jonathanw Riess , Eli Lilly , Charlesd Blanke , Emily Henderson , Karen Reckamp , Kenneth Grossmann , Neeraj Agarwal , Sepideh Gholami , University Of California , Clovis Oncology Inc , Foundation For The National Institutes Of Health , National Cancer Institute , University Of Utah , University Of Cincinnati Medical Center , Takeda Pharmaceutical Company Ltd , Merck Co Inc , University Of British Columbia , Office Of Research On Women Health , International Gmb , National Clinical Trials Network ,

UH Cancer Center helps boost research on minority populations | University of Hawaiʻi System News


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U.S., Blacks, Hispanics, American Indians/Alaska Natives, Asians and Native Hawaiian or other Pacific Islanders bear a disproportionate burden of disease, injury, premature death and disability. Cancer is just one example of the many health disparities that these groups face. The University of Hawaiʻi Cancer Center’s work with these populations has significantly improved ongoing efforts to reduce health disparities among these populations across Hawaiʻi and the Pacific in research that could impact other parts of the world.
Addressing disparities in minority communities
April is National Minority Cancer Awareness Month, a time to raise awareness about cancer health disparities among racial and ethnic minority populations. Cancer health disparities exist among minority populations for many reasons, one of which is lack of access to clinical trials in the community setting where they seek cancer care. To address the nation’s cancer disparities, the Nationa ....

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