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New approach to capture natural killer cells and harvest cancer-killing packets

Building on the promise of emerging therapies to deploy the body's "natural killer" immune cells to fight cancer, researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have gone one step further. ....

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Scientists 'farm' natural killer cells in novel cancer fighting approach

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IMAGE: Two large natural killer immune cells are surrounded by their much smaller exosomes on the NK-GO microfluidic chip developed at the University of Michigan.
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Credit: Image courtesy of Yoon-Tae Kang and Zeqi Niu.
Building on the promise of emerging therapies to deploy the body s natural killer immune cells to fight cancer, researchers at the University of Michigan Rogel Cancer Center and U-M College of Engineering have gone one step further.
They ve developed what is believed to be the first systematic way to catch natural killer cells and get them to release cancer-killing packets called exosomes. These nano-scale exosomes are thousands of times smaller than natural killer cells or NK cells for short and thus better able to penetrate cancer cells defenses. ....

United States , Gemma Purcell , Venkateshwarg Keshamouni , Sunitha Nagrath , Nithya Ramnath , Thomas Hadlock , Rishindra Reddy , Sarah Owen , Zeqi Niu , Mina Zeinali , Labyrinth Biotech Inc , National Institute Of Health , Rogel Cancer Center , National Science Foundation , Um College Of Engineering , University Of Michigan , Microfluidic Labyrinth Technology , Um Biointerfaces Institute , University Of Michigan Rogel Cancer Center , Michigan Rogel Cancer Center , Gum College , Yoon Tae Kang , Rogel Cancer , National Institute , Um Biointerfaces , Labyrinth Biotech ,

New Research in JNCCN Highlights Dangerous Disparities for Life-Saving Cancer Screening

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PLYMOUTH MEETING, Pa., Jan. 13, 2021 /PRNewswire/ New research in the January 2021 issue of
JNCCN Journal of the National Comprehensive Cancer Network finds more than a third of eligible people miss timely screening tests for colorectal cancer and at least a quarter appear to miss timely screening tests for breast and cervical cancers. The study comes from the University of Alberta, Faculty of Medicine and Dentistry in Alberta, Canada, with findings based on self-reported results from the Canadian Community Health Survey (CCHS) from 2007-2016. According to the author, the results also point to evidence of screening disparities being linked to lower socioeconomic status and identifiable minority race echoing a similar study conducted in the United States by the Centers for Disease Control. ....

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This mask-wearing appeal could work better than shaming

The findings may also have implications for encouraging people to get the new vaccine.
In a recent survey, people who said social distancing and COVID-safety guidelines violated their personal freedoms responded more positively to these ideas when they felt a loved one might be at risk of severe illness for COVID-19.
“Emphasizing the benefits of being a protector for others (instead of yourself) looks to be more effective in promoting greater adherence to recommended practices,” says author Lawrence An, associate professor of general medicine at Michigan Medicine and co-director of the University of Michigan’s Rogel Cancer Center’s Center for Health Communications Research. ....

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Health disparities in cancer and COVID-19 are caused by similar factors

Health disparities in cancer and COVID-19 are caused by similar factors
Income level, employment, housing location, medical insurance, education, tobacco and alcohol use, diet and obesity, access to medical care. These are some of the factors causing worse cancer outcomes in people who are Black.
The same factors are also causing worse outcomes from COVID-19 in this population.
The similarities between COVID-19 issues and cancer disparities is uncanny, says John M. Carethers, M.D., John G. Searle Professor and Chair of Internal Medicine at Michigan Medicine.
In cancer we are seeing in slow motion what has been observed rapidly with COVID - that the same conditions in our society put specific groups at risk for both. If we can fundamentally change socioeconomic inequality, we theoretically could reduce disparities in both diseases, says Carethers, who is a member of the University of Michigan Rogel Cancer Center. ....

United States , Johng Searle , Roberta Winn , Lisaa Newman , Johnm Carethers , Emily Henderson , University Of Michigan Rogel Cancer Center , Virginia Commonwealth University , Clinical Cancer Research , Internal Medicine , Michigan Rogel Cancer , Weill Cornell Medicine , ஒன்றுபட்டது மாநிலங்களில் , ரோபர்ட்டா வென்றது , லிசா புதியவர் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் ரோஜல் புற்றுநோய் மையம் , வர்ஜீனியா காமன்வெல்த் பல்கலைக்கழகம் , மருத்துவ புற்றுநோய் ஆராய்ச்சி , உள் மருந்து , மிச்சிகன் ரோஜல் புற்றுநோய் , வெயில் கார்னெல் மருந்து ,