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To Improve Immunotherapy, Researchers Look to Shift Immune Cells' Access to Sugar | Memorial Sloan Kettering Cancer Center


Summary
New research from Memorial Sloan Kettering scientists suggests that a way to improve immunotherapy is by altering immune cells’ access to sugar.
Cancer cells and immune cells share something in common: They both love sugar.
Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.
So, what happens when tumor cells and immune cells battle for access to the same supply of sugar? That’s the central question that Memorial Sloan Kettering researchers Taha Merghoub, Jedd Wolchok, and Roberta Zappasodi explore in a new study published February 15 in the journal ....

Taha Merghoub , Sloan Kettering , Roberta Zappasodi , Oncology Service , Ludwig Center , Pathogenesis Program , Parker Institute For Cancer Immunotherapy , Memorial Sloan Kettering , Jedd Wolchok , Immuno Oncology Service , Human Oncology , Parker Institute , Parker Institute Bridge Scholar , Weill Cornell , ஸ்லோன் கெட்டரிங் , புற்றுநோயியல் சேவை , லுட்விக் மையம் , பார்க்கர் நிறுவனம் க்கு புற்றுநோய் நோயெதிர்ப்பு சிகிச்சை , நினைவகம் ஸ்லோன் கெட்டரிங் , இம்யூனோ புற்றுநோயியல் சேவை , மனிதன் புற்றுநோயியல் , பார்க்கர் நிறுவனம் , பார்க்கர் நிறுவனம் பாலம் அறிஞர் , வெயில் கார்னெல் ,

New Global Coalition Aims to Eliminate Structural Barriers to Fight Cancer Crisis in Resource-Limited Countries in Africa


New Global Coalition Aims to Eliminate Structural Barriers to Fight Cancer Crisis in Resource-Limited Countries in Africa
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Collaboration on Implementation Science Research in Global Oncology awards $500,000 to eight country-specific pilot projects in quest to develop sustainable best practices
We have to look across the spectrum of cancer care capacity building and select certain projects to pilot in different countries, evaluate how they work and, if we, can replicate them in other countries,” said Ute Dugan, MD, co-founder of CIRGO.
CHICAGO (PRWEB)
February 09, 2021
A group of global oncology organizations have joined forces to establish the Collaboration on Implementation Science Research in Global Oncology (CIRGO) to improve the coordination of cancer care systems in low- and middle-income countries, particularly in Africa. ....

South Africa , United States , University Of California San Francisco , San Francisco , Ute Dugan , Dan Milner , Clinton Health Access Initiative , American Society For Clinical Oncology , Partners In Health , Ministry Of Health , International Cancer Research Partnership , Md Anderson Cancer Center , Wits Health Consortium , International Cancer Institute , Clinical Research , Bristol Myers Squibb , Parker Institute For Cancer Immunotherapy , Dmax Foundation , Ventures For Global Health , University Of Chicago Nigeria , National Comprehensive Cancer Network , Butaro Cancer Center , Bristol Myers Squibb Foundation , African Cancer Registry Network , World Health Organization , Africa Organization For Research ,

ImaginAb and NEUVOGEN Announce Licensing Agreement for CD8 ImmunoPET Technology


ImaginAb and NEUVOGEN Announce Licensing Agreement for CD8 ImmunoPET Technology
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LOS ANGELES and SAN DIEGO, Jan. 28, 2021 /PRNewswire/  ImaginAb Inc, a leading global provider of immuno-oncology imaging agents and NEUVOGEN, an immuno-oncology company developing next generation therapeutic whole cell cancer vaccines, announced they have signed a multi-year non-exclusive licensing agreement. 
Under the terms of the agreement, ImaginAb will work with NEUVOGEN to implement clinical doses of 89Zr CD8 Immuno-PET imaging agents into their therapeutic vaccine clinical trials, and provide technical and clinical support to NEUVOGEN s development teams.  ImaginAb will receive license fees and other contingent payments.  No other terms were disclosed.  ....

United States , San Diego , Jim Pallotta , Ian Wilson , Todd Binder , Christine Dusek , Cyrus Arman , Neuvogen Inc , Cycad Group , Imaginab Inc , Parker Institute For Cancer Immunotherapy , Raptor Group , Tumor Infiltrating Lymphocytes , Chief Executive Officer , Adage Capital , Parker Institute , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ , ஜிம் பல்லோட்டா , ஈயந் வில்சன் , டாட் பைண்டர் , கிறிஸ்டின் டுசேக் , சைரஸ் ஆர்மன் , சைக்காட் குழு , பார்க்கர் நிறுவனம் க்கு புற்றுநோய் நோயெதிர்ப்பு சிகிச்சை , ர்யாப்‌டர் குழு ,

Tmunity Announces Appointment of Jeffrey Leiden M.D., Ph.D. as Chairman of the Board of Directors


Press release content from Business Wire. The AP news staff was not involved in its creation.
Tmunity Announces Appointment of Jeffrey Leiden M.D., Ph.D. as Chairman of the Board of Directors
January 25, 2021 GMT
PHILADELPHIA (BUSINESS WIRE) Jan 25, 2021
Tmunity Therapeutics, Inc., a clinical-stage biotherapeutics company specifically designed to deliver on the bold promise to ‘uncancer the world’ by creating the best T cell medicines for solid tumor patients, today announced the appointment of Jeffrey Leiden, M.D., Ph.D., as Non-Executive Chairman of its Board of Directors.
“I am thrilled to welcome Jeff as Chair of our board of directors as 2021 will be a transformative year for Tmunity with our continued rapid advancement of our clinical and preclinical oncology portfolio. We wanted to bring on an equally transformative leader to chair our board, a physician-scientist who is passionate about translating scientific advances into breakthrough therapies ....

University Of Pennsylvania , United States , Harvard School Of Public Health , East Norriton , Julie Seidel , Jim Riley , Usman Oz Azam , Bruce Levine , Yangbing Zhao , Lisa Rivero , Vertex Pharmaceuticals , Elkanr Blout Professor Of Biological Sciences , Tmunity Therapeutics Inc , Professor Of Medicine At Harvard Medical School , American Academy Of Arts , Cardiovascular Research Institute , University Of Pennsylvania Penn , Massachusetts Mutual Life Insurance Company , University Of Chicago , Abbott Laboratories , Parker Institute For Cancer Immunotherapy , Quest Diagnostics , Jeffrey Leiden , Non Executive Chairman , Chief Executive Officer , Executive Chairman ,