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INOVIO's VGX-3100 Demonstrates Positive Phase 2 Efficacy In Treatment of Precancerous Vulvar Dysplasia Caused by HPV-16/18


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PLYMOUTH MEETING, Pa., Jan. 6, 2021 /PRNewswire/  INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases, cancer and HPV-associated diseases, today announced positive efficacy results for an open-label Phase 2 trial of VGX-3100 to treat HPV-16 and HPV-18-associated vulvar dysplasia. A 25% or more reduction in HPV-16/18-associated vulvar HSIL (high-grade squamous intraepithelial lesion) was observed for 63% of trial participants (12 of 19) treated with VGX-3100 at six months post-treatment. Three out of the 20 participants with histology data (15%) resolved their vulvar HSIL and had no HPV-16/18 virus detectable in the healed area. By comparison, the spontaneous resolution of vulvar HSIL caused by HPV-16/18 is estimated to be only 2%. The trial also showed VGX-3100 to be safe and well-tolerated. Based upon these results INOVIO is ....

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Top Life Sciences Startups to Watch in 2021

Top Life Sciences Startups to Watch in 2021
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Tmunity to Present at the 39th Annual J.P. Morgan Healthcare Conference


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​Tmunity Therapeutics, Inc., a private clinical-stage biotherapeutics company focused on saving and improving lives by delivering the full potential of next-generation T cell immunotherapy, today announced that President and CEO, Usman “Oz” Azam, will present at the 39th Annual J.P. Morgan Healthcare Conference on Tuesday, January 12, 2021 at 3:10 pm ET.
A live webcast of the presentation will be available on the “Events and Presentations” page of the Tmunity website at https://www.tmunity.com/events. Tmunity will maintain an archived replay of the webcast on the website for 30 days after the conference.
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About Tmunity Therapeutics
​Tmunity is a private, clinical-stage biotherapeutics company, focused on saving and improving lives by delivering the full potential of next-generation T-cell immunotherapy to patients with devastating diseases. Integrating a foundational ....

East Norriton , United States , Julie Seidel , Jim Riley , Usman Oz Azam , Bruce Levine , Yangbing Zhao , University Of Pennsylvania Penn , Tmunity Therapeutics Inc , Parker Institute For Cancer Immunotherapy , Tmunity Therapeutics , Healthcare Conference , About Tmunity , Carl June , Anne Chew , Parker Institute , கிழக்கு நோரிட்டன் , ஒன்றுபட்டது மாநிலங்களில் , ஜூலி சீடல் , ஜிம் ரைலி , உஸ்மேன் ஆஸ் அஸாம் , காயங்கள் லெவின் , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா பென் , பார்க்கர் நிறுவனம் க்கு புற்றுநோய் நோயெதிர்ப்பு சிகிச்சை , சுகாதாரம் மாநாடு , கார்ல் ஜூன் ,

INOVIO Announces Publication of Phase 1 Data from its COVID-19 DNA Vaccine Candidate, INO-4800 in The Lancet's EClinicalMedicine

PLYMOUTH MEETING, Pa., Dec. 24, 2020 /PRNewswire/ INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases ....

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INOVIO Announces Publication of Phase 1 Data from its COVID-19 DNA Vaccine Candidate, INO-4800 in Th


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24-Dec-2020
INOVIO Announces Publication of Phase 1 Data from its COVID-19 DNA Vaccine Candidate, INO-4800 in The Lancet s EClinicalMedicine
PLYMOUTH MEETING, Pa., Dec. 24, 2020 /PRNewswire/  INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases and cancer, today announced the publication of peer-reviewed Phase 1 clinical data from the first cohort of 40 participants for its COVID-19 DNA vaccine candidate, INO-4800, in
EClinicalMedicine, an open access clinical journal published by The Lancet.
The paper, titled Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: a preliminary report of an open-label, Phase 1 clinical trial, found that INO-4800 was immunogenic in all vaccinated subjects, effectively generating an immune response of humoral (including neutralizing antibodies) ....

South Korea , Ben Matone , Pablo Tebas , Stanley Plotkin , Jeff Richardson , Kaneka Eurogentec , J Joseph Kim , Walter Reed Army Institute Of Research , Us Department Of Defense , National Cancer Institute , National Institute Of Allergy , Plumbline Life Sciences , Laval University , Melinda Gates Foundation , Coalition For Epidemic Preparedness Innovations , University Of Texas , Hospital Of The University Pennsylvania , Defense Consortium , Parker Institute For Cancer Immunotherapy , Nuclear Defense , International Vaccine Institute , Korea National Institute For Health , Department Of Defense Do , Defense Health Agency , National Institutes Of Health , Global Coalition Advancing ,