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In a separate BMJ study, mothers who used prescription opioids in the first trimester had no increased risk of having a child with a birth defect, reported Brian Bateman, MD, of Brigham and Women s Hospital in Boston, and colleagues. Macrolides This nationwide cohort study found no association between the use of macrolide antibiotics during pregnancy and risk of major birth defects overall, or in the 12 organ-specific subgroups of birth defects examined, Andersson said in an email to MedPage Today. Neil Seligman, MD, a maternal-fetal medicine specialist at the University of Rochester Medical Center in New York, told MedPage Today that these results should provide reassurance to providers and patients that macrolide antibiotics can be safely taken in the first trimester. ....
email article Streamlined interim heart failure guidance, including newer therapies and acknowledging the changes in care wrought by the COVID-19 pandemic, was released by the American College of Cardiology (ACC). Angiotensin receptor-neprilysin inhibitors (ARNIs) and SGLT2 inhibitors were added to the treatment algorithms for new-onset and chronic heart failure in this update to the ACC s 2017 expert consensus decision pathway (ECDP) for treatment of heart failure with reduced ejection fraction (HFrEF). The document was meant to serve as interim guidance while the ACC drafts more comprehensive heart failure guidelines, according to the writing group chaired by Thomas Maddox, MD, MSc, of Washington University School of Medicine in St. Louis. ....
email article Greedy corporations, uncaring hospitals, individual miscreants, and a task force led by Jared Kushner were dinged Tuesday in the Lown Institute s annual Shkreli awards, a list of the top 10 worst offenders for 2020. Named after Martin Shkreli, the entrepreneur who unapologetically raised the price of an anti-parasitic drug by a factor of 56 in 2015 (now serving a federal prison term for unrelated crimes), the list of shame calls out what Vikas Saini, the institute s CEO, called pandemic profiteers. (Lown bills itself as a nonpartisan think tank advocating bold ideas for a just and caring system for health. ) Topping the list was the federal government itself and Jared Kushner, President s Trump s son-in-law, who led a personal protective equipment (PPE) procurement task force. The effort, called Project Airbridge, was to airlift PPE from overseas and bring it to the U.S. quickly, which it did. ....