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NIMH » Questions and Answers for the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) Study — Background


March 2007
A. STEP-BD is the largest, federally-funded treatment study ever conducted for bipolar disorder
1. It is a long-term outpatient study that enrolled 4,360 participants from 22 sites over seven years (1998 to 2005). STEP-BD was designed to find out which treatments, or combinations of treatments, are most effective for treating episodes of depression and mania and for preventing recurrent episodes in people with bipolar disorder. STEP-BD is different from typical clinical trials that test one potential new treatment. It is a broad research program that includes several different studies, each aimed at a different aspect of treatment for the illness.
Multiple treatments, including medications and psychotherapies, currently are available for people with bipolar disorder, but doctors are often uncertain which of these treatments actually work best for specific aspects of the illness. ....

United States , San Antonio , Baylor College Of Medicine , University Of Massachusetts Medical School , University Of Pennsylvania , Stephenr Wisniewski , Laurenb Marangell , Lamotrigine Lamictal , Jayendra Patel , Garys Sachs , Markd Fossey , Laszlo Gyulai , Terencea Ketter , Marks Bauer , Charles Bowden , Risperidone Risperdal , Peter Hauser , Paroxetine Paxil , Smith Kline , Josephr Calabrese , Kemal Sagduyu , Andrewa Nierenberg , Michael Allen , Systematic Treatment Enhancement Program For Bipolar Disorder , Harvard School Of Medicine , Stanford University School Of Medicine ,

New wireless system can restore communication and mobility in people with paralysis


New wireless system can restore communication and mobility in people with paralysis
Brain-computer interfaces (BCIs) are an emerging assistive technology, enabling people with paralysis to type on computer screens or manipulate robotic prostheses just by thinking about moving their own bodies. For years, investigational BCIs used in clinical trials have required cables to connect the sensing array in the brain to computers that decode the signals and use them to drive external devices.
Now, for the first time, BrainGate clinical trial participants with tetraplegia have demonstrated use of an intracortical wireless BCI with an external wireless transmitter. The system is capable of transmitting brain signals at single-neuron resolution and in full broadband fidelity without physically tethering the user to a decoding system. ....

Brown School , United States , Blackrock Microsystems , John Simeral , Sharlene Flesher , Leigh Hochberg , Arto Nurmikko , Emily Henderson , Providence Veterans Affairs Medical Center , Development Center , Brown School Of Engineering , Brown University , Brown Carney Institute For Brain Science , Va Rehabilitation Research , Biomedical Engineering , Study Lead Author , Engineering Professor , Carney Institute , Brain Science , Brown Wireless Device , Case Western Reserve , Massachusetts General , Massachusetts General Hospital , Clinical Trial , Veterans Affairs , பழுப்பு பள்ளி ,