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Bacteria May Be Key To Understanding Health of Aquatic Ecosystems


Rensselaer researchers to build biosensor capable of measuring critical nutrients in water
The surface of a pristine, transparent freshwater lake may not reveal to ecologists the reality of what’s occurring in its depths. Evaluating the cumulative effects of climate change, pollutants, acidification, or invasive species requires more precise methods. But even the most dynamic and sensitive sensors commonly used today are not always able to tell researchers what they need to know.
Engineers at Rensselaer Polytechnic Institute are teaming up with an unexpected ally – a metal-breathing bacterium called Shewanella oneidensis MR1 (S. oneidensis) – to try to dramatically improve biosensors for freshwater and marine aquatic ecosystems. ....

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Technique allows mapping of epigenetic information in single cells at scale


Date Time
Technique allows mapping of epigenetic information in single cells at scale
Decoding epigenomic information from individual cells from the mouse brain. Histones are attached to DNA as beads on a string, with different versions decorating the genome as “epigenetic stickers”, labelling which genes are turned on or off. The method single-cell CUT&Tag allows to examine tens of thousands of single cells at the same time to determine their histone profiles. Illustration by Amagoia Agirre.
Histones are tiny proteins that bind to DNA and hold information that can help turn on or off individual genes. Researchers at Karolinska Institutet have developed a technique that makes it possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells simultanously. The technique was applied to the mouse brain and can be used to study epigenetics at a single-cell level in other complex tissues. The study is published in Natu ....

Amagoia Agirre , Mandy Meijer , Karolinska Institutet , Mukund Kabbe , Marek Bartosovic , European Union Horizon , Innovation Programme , Swedish Society For Medical Research , Karolinska Institute , Alice Wallenberg Foundation , Swedish Brain Foundation , Ming Wai Lau Centre For Reparative Medicine , Swedish Cancer Society , Swedish Research Council , Department Of Medical Biochemistry , Medical Biochemistry , Vinnova Seal , Excellence Marie Sklodowska Curie Actions , Swedish Society , Medical Research , Ming Wai Lau Centre , Reparative Medicine , Nature Biotechnology , European Union , Multiple Sclerosis , Research Council ,

Governor-General opens new Deakin research building


Deakin
A new research building officially opened by the Governor-General, His Excellency David Hurley, will establish Deakin as the first university in Australia equipped to handle zone 4 classified, secret-rated defence research.
Located within the Geelong Future Economy Precinct at the University’s Waurn Ponds Campus, the $18million building will extend the capacity of Deakin’s Institute for Intelligent Systems Research and Innovation (IISRI) to build on its industry-leading research and development in the fields of motion simulation, robotics and haptics, defence systems, and modelling and simulation.
Now equipped with a Zone 4 capable classified secret-rated space, Deakin will become the first university in Australia to provide a highly secure research environment suitable for the Department of Defence and the defence industry. ....

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