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Jubilant Therapeutics Announces Research Collaboration with The Wistar Institute to Evaluate the Activity of Novel PAD4 Inhibitors to Reduce Clinical Severity of COVID-19

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BEDMINSTER, N.J., Jan. 15, 2021 /PRNewswire/ Jubilant Therapeutics Inc., a biopharmaceutical company advancing small molecule modulators to address unmet medical needs in oncology and autoimmune diseases, today announced a collaboration with The Wistar Institute, an international leader in biomedical research, to evaluate the ability of Peptidyl Arginine Deiminase 4 (PAD4) inhibitors provided by Jubilant Therapeutics to block neutrophil extracellular trap (NET) formation in the context of COVID-19 related cytokine storms.
PAD4 is an enzyme that catalyzes conversion of arginine to citrulline in proteins, including histones and is highly expressed in neutrophils. Histone citrullination has been implicated in Neutrophil Extracellular Trap (NET) formation and accumulating evidence suggests that NETs may be linked to the severity of COVID-19, as their formation is a result of pro-inflammatory cytokine release syndrome (CRS), or cytokine storms, produced by the body s im ....

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Genetic Toxicology Testing Market Is Projected To Reach USD 2.0 Billion By 2025 From USD 1.2 Billion In 2020, At A CAGR Of 10.2%

Genetic Toxicology Testing Market Is Projected To Reach USD 2.0 Billion By 2025 From USD 1.2 Billion In 2020, At A CAGR Of 10.2%
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Global Genetic Toxicology Testing Market is Growing at a CAGR of 10.3% by 2027

Global Genetic Toxicology Testing Market is Growing at a CAGR of 10.3% by 2027
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Worldwide Glacial Acetic Acid Industry to 2025 - Asia-Pacific Region to Dominate the Market

Worldwide Glacial Acetic Acid Industry to 2025 - Asia-Pacific Region to Dominate the Market
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