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Scientists atSt. JudeChildren’s Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial definitively showed that vincristine and dexamethasone pulses can be eliminated in patients with low-risk disease. The findings were published today in
The
Lancet Oncology.
Adding the chemotherapy vincristine plus a steroid (originally prednisone, and later dexamethasone) as pulse therapy for childhood ALL has been part of standard care since the 1970s. This is despite their being associated with neuropsychological side effects, neuropathy and other late effects. However, to date studies about the need for prolonged treatment with pulse therapy have been inconclusive. ....

Hong Kong , Hua Jiang , University Of Hong Kong , Hong Kong General , Hui Jiang , Hui Zhang , Jing Chen , Jingyan Tang , Aiguo Liu , Ju Gao , Yingchi Zhang , Wenyu Yang , Changda Liang , Minghua Yang , Kaili Pan , Runming Jin , Yongjun Fang , Chunfu Li , Yiping Zhu , Lirong Sun , Junj Yang , Jiaoyang Cai , Jie Yu , Xuedong Wu , Xiaowen Zhai , Ningling Wang ,

International collaboration helps refine treatment for childhood leukemia

International collaboration helps refine treatment for childhood leukemia
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

Hong Kong , Hua Jiang , University Of Hong Kong , Hong Kong General , Hui Jiang , Hui Zhang , Jing Chen , Jingyan Tang , Aiguo Liu , Ju Gao , Yingchi Zhang , Wenyu Yang , Changda Liang , Minghua Yang , Kaili Pan , Runming Jin , Yongjun Fang , Chunfu Li , Yiping Zhu , Lirong Sun , Junj Yang , Jiaoyang Cai , Jie Yu , Xuedong Wu , Xiaowen Zhai , Ningling Wang ,

Long-term effects of COVID-19 on kidney function – Authors' reply

Long-term effects of COVID-19 on kidney function – Authors' reply
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

Pierre Delanaye , Philipp Enghard , Jack Ma Foundation , Elsevier Ltd , Development Program Of China , Natural Science Foundation Of China , National Key Research , Sunshine Charity Foundation , Major Projects Of National Science , Development Of Pulmonary Tuberculosis , China Evergrande Group , Ping An Insurance Group , Clin Pract , View Large , Natural Science Foundation , Chinese Academy , Medical Sciences Innovation Fund , Medical Sciences , Development Program , Major Projects , National Science , New Drug Creation , Pulmonary Tuberculosis , Sino Biopharmaceutical , Ping An Insurance , New Sunshine Charity ,

The Lancet: Most patients hospitalised with COVID-19 have at least one symptom six months after falling ill, Wuhan follow-up study suggests

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Study of 1,733 patients first diagnosed in Wuhan (China) between January and May followed to June and September.
76% of COVID-19 patients have at least one symptom six months after symptom onset.
Fatigue or muscle weakness is the most common symptom, with sleep difficulties and anxiety or depression also frequently reported.
Lower antibodies against COVID-19 in patients six months after becoming ill compared with during acute infection raises concerns about the possibility of re-infection.
More than three quarters of COVID-19 patients have at least one ongoing symptom six months after initially becoming unwell, according to research published in
The Lancet.
The cohort study, looking at long-term effects of COVID-19 infection on people hospitalised in Wuhan, China, reveals that the most common symptom to persist is fatigue or muscle weakness (63% of patients), with patients also frequently experiencing sleep difficulties (26%). Anxiety or d ....

Jin Yin Tan , Giuseppe Remuzzi , Norberto Perico , Monica Cortinovis , Ricerche Farmacologiche Mario Negri , National Center , Union Medical College Foundation China Evergrande Group , Academy Of Medical Sciences , Jack Ma Foundation , Capital Medical University , Development Program Of China , Natural Science Foundation Of China , National Key Research , Sunshine Charity Foundation , Major Projects Of National Science , Development Of Pulmonary Tuberculosis , Ping An Insurance Group , Bin Cao , Respiratory Medicine , China Japan Friendship Hospital , Jin Yin Tan Hospital , Natural Science Foundation , Chinese Academy , Medical Sciences Innovation Fund , Medical Sciences , Development Program ,

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study

6-month consequences of COVID-19 in patients discharged from hospital: a cohort study
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

Union Medical College Foundation , National Natural Science Foundation Of China , National Key Research , Major Projects Of National Science , Development Of Pulmonary Tuberculosis , Development Program Of China , Jin Yin Tan Hospital , Lopinavir Trial , Natural Science Foundation , Chinese Academy , Medical Sciences Innovation Fund , Medical Sciences , Development Program , Major Projects , National Science , New Drug Creation , Pulmonary Tuberculosis , Peking Union Medical College , தொழிற்சங்கம் மருத்துவ கல்லூரி அடித்தளம் , தேசிய இயற்கை அறிவியல் அடித்தளம் ஆஃப் சீனா , தேசிய விசை ஆராய்ச்சி , முக்கிய ப்ராஜெக்ட்ஸ் ஆஃப் தேசிய அறிவியல் , வளர்ச்சி ஆஃப் நுரையீரல் காசநோய் , வளர்ச்சி ப்ரோக்ர்யாம் ஆஃப் சீனா , ஜின் யின் பழுப்பு மருத்துவமனை , இயற்கை அறிவியல் அடித்தளம் ,