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Frontiers | Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed for twelve inflammatory cytokines using ELISA. Serotyping shows 14 DENV-1, 22 DENV-2, 7 DENV-3 and 33 DENV-4, where DENV-4 was predominant. Among seventy-six, forty-two isolates were successfully sequenced for C-prM region and grouped. A lineage shift was observed in DENV-4 genotype. Irrespective of serotypes, IFNγ was significantly elevated than control and in primary infection indicating its ro ....

United States , United Kingdom , New Delhi , Tamil Nadu , Sri Lanka , Republic Of , North Western , City Of , Andaman And Nicobar Islands , Saudi Arabia , Gonzalez Mateos , Flores Aguilar , Flavivirus Serocomplex Cross , Vellore Cecilia , Cladec Cecilia , Lakshmana Rao , Alwin Prem Anand , Andrea Wizenmann , Cruz Hernandez , Oswaldo Cruz , Gowri Sankar , Triuppur Alagarasu , Pondicherry Hoti , Waal Malefyt , Lopez Martinez , Nadu Manakkadan ,

"생소해서 불안해"…50대, '모더나 백신'에 대해 알아둘 것은?


세계일보
입력 : 2021-07-30 16:15:20 수정 : 2021-07-30 18:05:41
인쇄메일글씨 크기 선택가장 작은 크기 글자한 단계 작은 크기 글자기본 크기 글자한 단계 큰 크기 글자가장 큰 크기 글자
50대 연령층, 코로나 백신 접종 시작…화이자·모더나 등 백신 맞아
코로나 유증상 감염 예방 94.1%…변이 바이러스 예방 효과 뛰어나
접종 후 이상반응 다른 백신과 비슷…얼굴 부종 등 나타날 가능성
‘심근염·심낭염’ 특히 주의…의심 증상 발생시 신속히 병원서 치료
백신 접종 전후 금주해야…타이레놀, 술과 함께 복용시 간에 부담
만 55∼59세(1962∼1966년생) 약 304만명에 대한 코로나19 예방접종이 시작된 26일 오전 광주 북구의 한 병원에서 대상자들에게 접종할 모더나 백신을 의료진이 준비하고 있다. 연합뉴스
 
50대에 대한 신 ....

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