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AMP recommends minimum set of pharmacogenetic alleles to guide clinical CYP2D6 genotype testing, pro


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ROCKVILLE, Md. - June 10, 2021 - The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care. The manuscript, Recommendations for Clinical CYP2D6 Genotyping Allele Selection: A Joint Consensus Recommendation of the Association for Molecular Pathology, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, and European Society for Pharmacogenomics and Personalized Therapy, was released online ahead of publication in The
Journal of Molecular Diagnostics. ....

United States , Antoniar Sepulveda , College Of American Pathologists , Indiana University School Of Medicine , Amp Pgx Working Group , Pharmacogenetics Pgx Working Group , Association For Molecular Pathology , Canadian Pharmacogenomics Network For Drug Safety , Dutch Pharmacogenetics Working Group , Amp Pgx Working Group Chair , Clinical Pharmacogenetics Implementation Consortium , European Society For Pharmacogenomics , American College Of Medical Genetics , Molecular Pathology , Allele Selection , Joint Consensus Recommendation , American Pathologists , Royal Dutch Pharmacists Association , European Society , Personalized Therapy , Working Group , Canadian Pharmacogenomics Network , Drug Safety , American College , Medical Genetics , Molecular Genetics Laboratories ,

For better drugs, diversify clinical trials


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Summary
COVID-19 has highlighted the devastating disparities that exist for Black, Latinx, and Indigenous people in health care and medicine in the United States and other parts of the world. As a result, the importance of ethnic diversity in clinical trials has entered public discourse. This moral issue is enough to warrant elevation. But there are also scientific considerations because a lack of diversity in clinical trials hinders the ability to fully understand variation and predict drug outcomes across populations, including those most hard-hit by a disease. ....

United States , Drug Administration , Clinical Pharmacogenetics Implementation Consortium , African American , European Americans , ஒன்றுபட்டது மாநிலங்களில் , மருத்துவ மருந்தியல் செயல்படுத்தல் கூட்டமைப்பு , ஐரோப்பிய அமெரிக்கர்கள் ,