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SynDevRx Announces Research Collaboration with Maine Medical Center Research Institute to Study the Effects of SDX-7320 In Obesity-Accelerated Multiple Myeloma Models

Kojin Therapeutics Debuts to Solve Difficult Diseases Through Cell Behavior


Published: Jun 09, 2021
By Mark Terry
Kojin Therapeutics
launched with a $60 million Series A to initially focus on oncology and cell state biology. The round was led by Polaris Partners, Newpath Partners, and Cathay Health, affiliated to Cathay Capital. Participants included Leaps by Bayer, AbbVie, Eventide Asset Management, Alexandria, the Dana-Farber Cancer Institute’s Binney Street Capital, and several family offices.
The approach came out of the
laboratoryof Stuart Schreiber, Harvard University professor and co-founder of the Broad Institute. Co-founders of Kojin include Benjamin Cravatt, Stephanie Dougan and Vasanthi Viswanathan. The company’s technology is ferroptosis-based drug discovery, which is to say, iron-dependent cell death. Kojin says that difficult-to-treat diseases, which includes drug-resistant cancers, involve diseased cells that are sensitive to ferroptosis. ....

United States , Al Iskandariyah , Harvard University , Dana Farber Cancer Institute , Jurgen Eckhardt , Amir Nashat , Benjamin Cravatt , Stephanie Dougan , Joel Barrish , Steve Davidsen , Nagesh Mahanthappa , Susan Langer , Vasanthi Viswanathan , Nortonb Gilula , Stuart Schreiber , Kay Ahn , Sean Morrison , Scripps Research Institute , Broad Institute , Sarcoma Center At Dana Farber , Harvard Medical School , Ludwig Center At Dana Farber Harvard Cancer , Cathay Health , Children Medical Center Research Institute , Department Of Chemistry , Schreiber Lab ,

Communicating Scientific Uncertainty About the COVID-19 Pandemic: Online Experimental Study of an Uncertainty-Normalizing Strategy


Han, Scharnetzki, Lary, Waterston); University of Iowa Carver College of Medicine (
Scherer); University of Utah (
Fagerlin); Oregon Health and Science University (
Dieckmann)
.a strategy aimed at normalizing uncertainty as an expected state of affairs was effective in reducing at least some aversive psychological responses to the communication of uncertainty, whereas widely used alternative strategies aimed at promoting hope and prosocial values had no such effect.
Expert guidelines on crisis communication stress the importance of acknowledging uncertainty - a defining feature of public health crises such as COVID-19 - in order to foster public accountability and trust. However, the communication of scientific uncertainty has the potential to promote negative cognitive, emotional, and behavioural responses, such as heightened risk perceptions, emotional distress, and decision avoidance. This study evaluates whether a communication strategy emphasising that ....

United States , Salt Lake City , Paul Kj Han , Alistair Thorpe , Leob Waterston , Christine Lary , Elizabeth Scharnetzki , Aaronm Scherer , Angela Fagerlin , Nathanf Dieckmann , Maine Medical Center Research Institute Han , Salt Lake City Va Center , University Of Utah Thorpe , Science University Dieckmann , Oregon Health , Medical Center Research Institute , Iowa Carver College , Informatics Decision Enhancement , Science University , Hiv Aids , United Nations , ஒன்றுபட்டது மாநிலங்களில் , உப்பு ஏரி நகரம் , பால் க்ஜ் ஹான் , அலிஸ்டர் தோர்ப் , ஓரிகந் ஆரோக்கியம் ,

'Jumping' genes can prevent blood cancers: Study


Jumping genes can prevent blood cancers: Study
​ By
IANS
|
​ 4 Views
Gallbladder, biliary tract cancer cases up 76% in 3 decades. Image Source: IANS News
New York, April 9 : US scientists have found that transposons, also known as jumping genes, can protect against certain blood cancers and help develop new therapeutic targets.
Transposons are DNA sequences that can move, or jump, from one location in the genome to another when activated. These jumping genes are a source of genetic mutations responsible for a number of human diseases.
The findings, published in the journal Nature Genetics, can help predict how patients will respond to cancer therapies and find new therapeutic targets for acute myeloid leukemia (AML) the deadliest type of blood cancer in adults and children. ....

New York , United States , Jian Xu , Children Medical Center Research Institute , University Of Texas Southwestern , Nature Genetics , Medical Center Research Institute , Texas Southwestern , Associate Professor , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , ஜியான் ஐயூ , குழந்தைகள் மருத்துவ மையம் ஆராய்ச்சி நிறுவனம் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் தென்மேற்கு , இயற்கை ஜெநெடிக்ஸ் , மருத்துவ மையம் ஆராய்ச்சி நிறுவனம் , டெக்சாஸ் தென்மேற்கு , இணை ப்ரொஃபெஸர் ,