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People Aged Over 105 may Have More Efficient DNA Repair


People Aged Over 105 may Have More Efficient DNA Repair
by Angela Mohan on 
May 5, 2021 at 8:54 AM
eLife.
These people have had their genomes decoded in a detailed manner first time, providing clues as to why they live so long.br>
Aging is a common risk factor for several chronic diseases and conditions, explains Paolo Garagnani, Associate Professor at the Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy, and a first author of the study.
We chose to study the genetics of a group of people who lived beyond 105 years old and compare them with a group of younger adults from the same area in Italy, as people in this younger age group tend to avoid many age-related diseases and therefore represent the best example of healthy aging. ....

Cristina Giuliani , Massimo Delledonne , Claudio Franceschi , Paolo Garagnani , Environmental Sciences , University Of Verona , Department Of Experimental , Laboratory Of Molecular Anthropology , University Of Bologna , Associate Professor , Specialty Medicine , Senior Assistant Professor , Molecular Anthropology , Full Professor , Professor Emeritus , Free Radicals Cell , Printinggenetic Testing , Diseasesepigeneticsoxidative Stress , கிறிஸ்டினா கியுலியானி , கிளாடியோ பிரான்செச்சி , சுற்றுச்சூழல் அறிவியல் , பல்கலைக்கழகம் ஆஃப் வெரோனா , துறை ஆஃப் சோதனை , பல்கலைக்கழகம் ஆஃப் போலோக்னா , இணை ப்ரொஃபெஸர் , சிறப்பு மருந்து ,

Do people aged 105 and over live longer because they have more efficient DNA repair?


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Researchers have found that people who live beyond 105 years tend to have a unique genetic background that makes their bodies more efficient at repairing DNA, according to a study published today in
eLife.
This is the first time that people with extreme longevity have had their genomes decoded in such detail, providing clues as to why they live so long and manage to avoid age-related diseases.
Aging is a common risk factor for several chronic diseases and conditions, explains Paolo Garagnani, Associate Professor at the Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy, and a first author of the study. We chose to study the genetics of a group of people who lived beyond 105 years old and compare them with a group of younger adults from the same area in Italy, as people in this younger age group tend to avoid many age-related diseases and therefore represent the best example of healthy aging. ....

Cristina Giuliani , Massimo Delledonne , Claudio Franceschi , Emily Packer , Paolo Garagnani , Environmental Sciences , Research In Lausanne , University Of Verona , Department Of Experimental , Laboratory Of Molecular Anthropology , University Of Bologna , Associate Professor , Specialty Medicine , Patrick Descombes , Senior Assistant Professor , Molecular Anthropology , Full Professor , Professor Emeritus , Special Issue , Media Relations Manager , Medicine Health , கிறிஸ்டினா கியுலியானி , கிளாடியோ பிரான்செச்சி , எமிலி ப்யாகர் , சுற்றுச்சூழல் அறிவியல் , பல்கலைக்கழகம் ஆஃப் வெரோனா ,

Researchers dig up secrets of gut microbiomes from thousands of years ago


Researchers dig up secrets of gut microbiomes from thousands of years ago
What do you get when an archeologist and a gut microbiome researcher collaborate? Ancient poop.
An international research team was able to analyze DNA from 50,000-year-old fecal sediments sampled at the archaeological site of El Salt, near Alicante, Spain, a location where Neanderthals lived before they disappeared from the scene. The fecal material the oldest available to date was excavated by an archeologist from the University of La Laguna, Campus de Guajara, Spain, and then sent to the University of Bologna for the analysis.
The study, published in the journal  ....

United States , La Laguna , Castilla La Manacha , Marco Candela , Silvia Turroni , Simone Rampelli , Microbiome Research In Norman , University Of La Laguna , Department Of Pharmacy , Biotechnology Of The University Bologna , University Of Bologna , Campus De Guajara , Communication Biology , Molecular Anthropology , Microbiome Research , Illumina Nextseq , Nutraingredients United States , Professor Candela , Gut Digestive Health , Immune Support , Probiotics Amp Prebiotics , Gut Microbiome , ஒன்றுபட்டது மாநிலங்களில் , லா லகுனா , மார்கோ மெழுகுவர்த்தி , சிமோன் ராம்பெல்லி ,