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Study shows how mutant huntingtin protein triggers brain cell death

Study shows how mutant huntingtin protein triggers brain cell death
In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington s disease, raising high hopes for a quick cure. Yet today, there s still no approved treatment.
One difficulty has been a limited understanding of how the mutant huntingtin protein sets off brain cell death, says neuroscientist Srinivasa Subramaniam, Ph.D., of Scripps Research, Florida.
In a new study published in
Nature Communications on Friday, Subramaniam s group has shown that the mutated huntingtin protein slows brain cells protein-building machines, called ribosomes.
The ribosome has to keep moving along to build the proteins, but in Huntington s disease, the ribosome is slowed. The difference maybe two, three, four-fold slower. That makes all the difference. ....

United States , Srinivasa Subramaniam , Emily Henderson , Scripps Research , Scripps Research Institute , Nature Communications On , Nature Communications , Huntington 39s Disease , Brain Cell , Cell Death , Protein Synthesis , ஒன்றுபட்டது மாநிலங்களில் , ஸ்ரீநிவாச சுப்ரமணியம் , எமிலி ஹென்டர்சன் , ஸ்கிரிப்ட்கள் ஆராய்ச்சி , ஸ்கிரிப்ட்கள் ஆராய்ச்சி நிறுவனம் , இயற்கை தகவல்தொடர்புகள் ஆன் , இயற்கை தகவல்தொடர்புகள் , மூளை செல் , செல் இறப்பு , ப்ரோடீந் தொகுப்பு ,

Welcome To IANS Live - ENTERTAINMENT - Amit Shah's biography released in Assamese

Photo Credit: IANS
IANSLive
Guwahati, March 8 (IANS) A biography of Union Home Minister Amit Shah, which has been translated by Assam Minister Himanta Biswa Sarma from English to Assamese, was released here on Monday.
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© 2021 IANS India Private Limited. All Rights Reserved.
The reproduction of the story/photograph in any form will be liable for legal action.
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Update: 08-March-2021 ....

Amit Shah , Himanta Biswa Sarma , Union Home , News Service , India Private , Union Home Minister Amit Shah , Assam Minister Himanta Biswa Sarma , All Rights , அமித் ஷா , ஹீமந்த பிஸ்வா சர்மா , தொழிற்சங்கம் வீடு , செய்தி சேவை , இந்தியா ப்ரைவேட் , தொழிற்சங்கம் வீடு அமைச்சர் அமித் ஷா , அசாம் அமைச்சர் ஹீமந்த பிஸ்வா சர்மா , அனைத்தும் உரிமைகள் ,

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection
Apoptosis is a form of programmed cell death, which occurs in cells that are irreparably damaged or in cells infected by some viruses. This mechanism is extremely important in limiting a virus’s replication and its spread to other neighboring cells.
A new paper in the journal
Lifepresents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.
Colorized scanning electron micrograph of an apoptotic cell (blue) infected with SARS-COV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Image Credit: NIAID / Flickr ....

United States , Fort Detrick , Liji Thomas , Research Facility , Image Credit , Junn Terminal , Porcine Epidemic Diarrhea Virus , Corona Virus , Coronavirus Disease Covid 19 , Sars Cov 2 , Cell Cycle , Cell Death , Programmed Cell Death , Ribonucleic Acid , Transcription Factors , ஒன்றுபட்டது மாநிலங்களில் , கோட்டை டெட்ரிக் , ஆராய்ச்சி வசதி , படம் கடன் , கொரோனா வைரஸ் , செல் மிதிவண்டி , செல் இறப்பு , எதிர் மின்னணு , வளர்சிதை மாற்றம் , ப்ரோக்ராம்ட் செல் இறப்பு , படியெடுத்தல் காரணிகள் ,

7 Issues of International Women's Writing to Read on #IWD2021

7 Issues of International Women’s Writing to Read on #IWD2021
Image: Farazeh Syed, Attire (cropped), acrylic on canvas, 4 x 5 ft, 2016. By arrangement with the artist.
Happy International Women s Day! In celebration of this special day, we ve selected seven outstanding issues of women s writing in translation from the WWB archives. Featuring work from Sudan, Hungary, Taiwan, Tunisia, China, and more, these issues offer a glimpse of the range and diversity of contemporary women s writing from around the globe.
Image: Yasmeen Abdullah, “The Butterfly Effect.” By arrangement with the artist.
Very little writing from Sudan is translated into English, and even less of it is written by women. In this issue, guest editor Sawad Hussain introduces five female Sudanese novelists you should know, all of whom made their English-language debut in WWB. ....

Zhao Ying , Zeinab Belail Al , Farazeh Syed , Demna Belhaj Yahia , Lionel Messi , Maria Chilf , Igiaba Scego , Mary Sibande , Qiu Miaojin , Haider Shahbaz , Eliza Griswold , Sam Balye , Houda Ghorbel , Faccetta Nera , Bonnie Huie , Sawad Hussain , Emma Ramadan , Jeremy Tiang , Khalida Hussain , Yasmeen Abdullah , Anthony Shugaar , Nesrin Amin , International Women Day , International Women , Butterfly Effect , Zeinab Belail ,

Daily Reading for Tuesday, March 9th, 2021 - Bible

The daily readings are taken from the lectionary which divides much of the Bible into three years worth of readings. If you complete the daily readings each day for three years, you will read 15 percent of the Old Testament and 71 percent of the New Testament. ....

Keith Fournier , Your Catholic Voice Foundation , Deacon Keith , Catholic Online , Catholic Voice Foundation , Internal Revenue , Federal Tax Identification Number , கேய்ட் ஃபோர்னியர் , உங்கள் கத்தோலிக் குரல் அடித்தளம் , டீக்கன் கேய்ட் , கத்தோலிக் நிகழ்நிலை , கத்தோலிக் குரல் அடித்தளம் , உள் வருவாய் , கூட்டாட்சியின் வரி அடையாளம் எண் , கடையில் பொருட்கள் வாங்குதல் ,