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Over $17M to support world leading medical research at Monash

A project to commercialise the world's first fully implantable artificial heart and research into rare cancers and diseases such as silicosis are among. ....

South Australia , New South Wales , Julie Brimblecombe , David Kaye , Marc Parlange , Cheryce Harrison , Andrew Wei , Alisa Pedrana , Heather Cleland , Shaun Gregory , Joseph Doyle , Michelle Tate , Orla Morrissey , Michelle Giles , Erica Wood , National Health , Monash University , Monash Centre For Health Research , Environmental Health , Central Clinical School , University Of Sydney , Department Of Neuroscience , Skin Bioengineering Laboratory , Monash Centre For Occupational , Hudson Institute , Burnet Institute ,

Drug treatment benefit for pregnant women with MS

Monash University
A recent study by Monash University has highlighted the benefit for pregnant women with MS who continue with a disease modifying treatment during and after pregnancy.
Using data from the international MSBase registry, the findings published in Neurology, revealed that women with MS who continued to take natalizumab (Tysabri) through and after their pregnancy had a decrease in relapse rates by up to 89 per cent. In contrast, women with MS who stopped taking natalizumab (Tysabri) and another therapy, fingolimod (Gilenya), before conception had an increase in relapse rates.
Led by senior research fellow Dr Vilija Jokubaitis from the department of neuroscience at Monash Central Clinical School, the study is the first to show how well the disease can be controlled through and after pregnancy if women are appropriately managed on this therapy. ....

South Australia , Adriana Condello , Vilija Jokubaitis , Iwei Yeh , Ms Research Australia , Monash University , Msbase International Registry , Dr Julia Morahan Is Head Of Research , Monash Central Clinical School , International Registry , Julia Morahan , தெற்கு ஆஸ்திரேலியா , வெய் ஆமாம் , செல்வி ஆராய்ச்சி ஆஸ்திரேலியா , மோனாஷ் பல்கலைக்கழகம் , மோனாஷ் மைய மருத்துவ பள்ளி , சர்வதேச பதிவு , ஜூலியா மோர்தன் ,

Researchers discover how to fix a 'broken heart'

Researchers discover how to fix a broken heart
Newshub
3 hrs ago
© Getty.
It turns out you can literally die from a broken heart.
If you ve ever been savagely dumped or suffered the loss of a loved one, you ll know one of the only ways to heal a metaphorical broken heart is time.
But what about when that broken heart has real, physical effects?
Takotsubo cardiomyopathy, otherwise known as broken heart syndrome , was first discovered in the 1990s. It s characterised by the heart s left ventricle losing function and is typically caused by emotional or physical stress.
The condition mimics a heart attack with chest pain, shortness of breath and irregular heartbeat. It also almost exclusively affects women, especially after menopause, with new research suggesting that up to eight percent of women suspected of having a heart attack may have this disorder. ....

United Kingdom , United States , Sam El Osta , Monash Central Clinical School , Signal Transduction , Targeted Therapy , Professor Sam El Osta , Monash Central Clinical , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது மாநிலங்களில் , மோனாஷ் மைய மருத்துவ பள்ளி , சமிக்ஞை கடத்தல் , இலக்கு சிகிச்சை , மோனாஷ் மைய மருத்துவ ,

Researchers find a way to mend a broken heart

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A Monash University study has uncovered for the first time a way to prevent and reverse damage caused by broken-heart syndrome, also known as Takotsubo cardiomyopathy.
Using mouse models, the pre-clinical study published in the acclaimed journal
Signal Transduction and Targeted Therapy, has shown the cardioprotective benefit of a drug called Suberanilohydroxamic acid, or SAHA, dramatically improved cardiac health and reversed the broken-heart. The landmark study used SAHA to target genes and is a world first for Takotsubo cardiomyopathy.
SAHA, currently used for cancer treatment, is approved by the US Food and Drug Administration (FDA) and Australian Therapeutic Goods Administration (TGA), works by providing a protective benefit to genes and in particular the acetylation/deacetylation (Ac/Dc) index, an important process that regulates gene expression. ....

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Food science potential: How fibre-rich formulations could minimise gut and kidney harm caused by processed foods

Food science potential: How fibre-rich formulations could minimise gut and kidney harm caused by processed foods
Scientists have shown how shown how chemical compounds found in highly processed foods play a role in chronic kidney disease, and are now turning their attention to new formulations and prebiotic ingredients that could help minimise the risk.
A recent study by Australia s Monash University has shown that a diet high in processed foods brings on leaky gut syndrome, which in turn increases the risk of kidney disease.
In particular, the findings revealed that certain harmful chemical compounds called Advanced Glycation End Products (AGEs), triggered by a process called the Maillard reaction, switch on the body s danger signals leading to an inflammatory response and chronic kidney disease. ....

South Australia , Jane Muir , Melindat Coughlan , Elif Ekinci , Melinda Coughlan , Department Of Gastroenterology , University Of Melbourne , Diabetes At Austin Hospital Melbourne Medical School , Australia Monash University , Monash Central Clinical School , Monash University , Advanced Glycation End Products , Science Advances , Associate Professor Melinda Coughlan , Associate Professor , Associate Professor Jane Muir , Associate Professor Elif Ekinci , Melbourne Medical School , தெற்கு ஆஸ்திரேலியா , ஜேன் ம்யூவைர் , மெலிண்டா இருமல் , துறை ஆஃப் இரைப்பை குடல் , பல்கலைக்கழகம் ஆஃப் மெல்போர்ன் , நீரிழிவு நோய் இல் ஆஸ்டின் மருத்துவமனை மெல்போர்ன் மருத்துவ பள்ளி , ஆஸ்திரேலியா மோனாஷ் பல்கலைக்கழகம் , மோனாஷ் மைய மருத்துவ பள்ளி ,