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Be 'Mindful' of TAVI Unknowns in Younger Patients, Experts Urge


June 09, 2021
Transcatheter aortic valve implantation is approved in the United States for low-risk patients with severe aortic stenosis, without an age threshold. As the authors of a new review point out, though, much is still unknown about how youth can impact outcomes and future options.
Low risk and younger age are categories that should not be conflated, they urge. “The pivotal TAVR trials in low-risk patients have, so far, demonstrated excellent clinical outcomes. However, these results should be extrapolated to younger patients with caution.”
Toby Rogers, MD, PhD (MedStar Washington Hospital Center, Washington, DC, and National Institutes of Health, Bethesda, MD), who led the paper along with Charan Yerasi, MD (MedStar Washington Hospital Center), stressed a similar point to TCTMD. ....

Medstar Washington Hospital Center , District Of Columbia , United States , United Kingdom , Kendra Grubb , Charan Yerasi , Toby Rogers , Benoy Shah , Md Emory University , British Heart Valve Society , National Institutes Of Health , Md Medstar Washington Hospital Center , Drug Administration , Phd Medstar Washington Hospital Center , National Institutes , Cardiovascular Interventions , Emory University , Evolut Low Risk , Evolut Low Risk Bicuspid , Southampton General Hospital , British Heart Valve , Evolut Low , North America , மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் ,

Chinese Registry Supports Prolonged DAPT Following PCI for ACS


May 03, 2021
Long-term dual antiplatelet therapy (DAPT) reduces ischemic events without a trade-off in bleeding compared with shorter durations among ACS patients who undergo PCI, according to new registry data from China.
The findings, released at the virtual Society for Cardiovascular Angiography and Interventions (SCAI) 2021 meeting, are slightly out of step with the TWILIGHT ACS substudy, which indicated a shorter duration of DAPT followed by ticagrelor monotherapy lowers bleeding risk in these patients without increasing ischemic events. In the Chinese registry, DAPT primarily consisted of clopidogrel and aspirin.
“To the best of our knowledge, this is the first report investigating the feasibility and safety of long-term DAPT for high-risk ‘TWILIGHT-like’ patients with ACS treated with DES,” Hao-Yu Wang, MD (Fuwai Hospital, Beijing, China), said in his presentation. “These results suggested that prolonged DAPT in ACS patients who present with a particul ....

Medstar Washington Hospital Center , District Of Columbia , United States , Zhaoyu Wang , Bonnie Weiner , David Cox , Md Brown University , Md Medstar Washington Hospital Center , Md Lehigh Valley Health Network , Society For Cardiovascular Angiography , Cardiovascular Angiography , Fuwai Hospital , Cardiovascular Interventions , Lehigh Valley Health Network , Brown University , Ron Waksman , Saint Vincent Hospital , மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் , போனி வீனர் , டேவிட் காக்ஸ் , ம்ட் பழுப்பு பல்கலைக்கழகம் , ம்ட் மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , சமூகம் க்கு இருதய ஆஞ்சியோகிராபி , இருதய ஆஞ்சியோகிராபி ,

Cardiogenic Shock: Protocols, Clear Definitions Advance the Field


April 30, 2021
Two new studies document the progress that’s been made in creating a consistent approach to cardiogenic shock care, and point to new directions as the field evolves. Both were released this week in a late-breaking session of the Society for Cardiovascular Angiography and Interventions (SCAI) 2021 virtual meeting.
Jacob Jentzer, MD (Mayo Clinic, Rochester, MN), presented pooled data confirming that SCAI’s classification system for shock severity tracks closely with mortality risk. Babar Basir, DO (Henry Ford Health System, Detroit, MI), shared final results from the National Cardiogenic Shock Initiative (NCSI) showing that an algorithm emphasizing early use of mechanical circulatory support can offer better survival for patients with acute MI complicated by cardiogenic shock (AMICS). ....

Medstar Washington Hospital Center , District Of Columbia , United States , Jacob Jentzer , Ron Waksman , Impella Abiomed , Behnamn Tehrani , Bonnie Weiner , Falls Church , Do Henry Ford Health System , Vascular Institute , Md Medstar Washington Hospital Center , Society For Cardiovascular Angiography , National Cardiogenic Shock Initiative , Cardiovascular Angiography , Mayo Clinic , Henry Ford Health System , Inova Heart , Shock Stage , மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் , போனி வீனர் , விழும் தேவாலயம் , வாஸ்குலர் நிறுவனம் , ம்ட் மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் ,

Low Mortality and Stroke Rates With BASILICA Pre-TAVI, Registry Shows


Photo Credit: Ron Waksman/Medstar Washington Hospital Center
The BASILICA procedure, which involves the intentional laceration of a preexisting aortic leaflet prior to TAVI in order to prevent coronary obstruction, can be safely performed in the vast majority of patients, according to new data from an international registry.
Among 214 patients undergoing BASILICA at 25 centers, the rate of death at 30 days was 2.8%, as was the rate of stroke, and just one patient (0.5%) had a disabling stroke.
Senior investigator Ron Waksman, MD (MedStar Washington Hospital Center, Washington, DC), said BASILICA offers a “unique solution” to patients at high risk for coronary obstruction with TAVI, one that isn’t associated with increased cost. “We wanted to prove that BASILICA was safe, number one, and feasible, number two, and effective,” Waksman told TCTMD. ....

University Of Washington , United States , Medstar Washington Hospital Center , District Of Columbia , Danny Dvir , Andrew Goldsweig , Ron Waksman , Jaffar Khan , Md University Of Washington , Phd National Heart , Md Medstar Washington Hospital Center , Blood Institute , Md University Of Nebraska Medical Center , National Heart , Cardiovascular Interventions , Nebraska Medical Center , Coronary Obstruction , Medstar Aortic Valve Stenosis , பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் , ஒன்றுபட்டது மாநிலங்களில் , மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் , மாவட்டம் ஆஃப் கொலம்பியா , ஜாஃபர் காந் , ம்ட் பல்கலைக்கழகம் ஆஃப் வாஷிங்டன் , ஃப்ட் தேசிய இதயம் , ம்ட் மெட்ஸ்டார் வாஷிங்டன் மருத்துவமனை மையம் ,