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Amgen Reports Revenue, Earnings Increase, But Shares Fall on Lower Guidance | San Fernando Valley Business Journal

Amgen Inc. beat expectations on revenue and earnings, but issued lower guidance for the rest of the year, sending shares lower.
The Thousand Oaks biotechnology company reported revenue of $6.5 billion, a 5.2 percent increase year-over-year that was driven by higher unit demand and partially offset by lower net selling prices.
Amgen’s adjusted earnings increased 4 percent to $2.5 billion, or $4.38 per share, benefiting from increased revenues and fewer average shares outstanding because of a buyback program. Wall Street analysts expected $4.10 a share on average, according to Refinitiv.
“As we look to the balance of the year, we are excited to be launching Lumakras, a first-in-class lung cancer treatment, and advancing a robust pipeline of potential new medicines to meet the demands of patients around the world,” Robert Bradway, Amgen’s chief executive, said in a statement. ....

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Eying eczema, Amgen pays $400M to co-develop Phase 3-ready Kyowa Kirin drug

Amgen is paying Kyowa Kirin $400 million to share in the development of a drug that could offer a new approach to treating atopic dermatitis, a form of eczema. The deal comes months after Japan-based Kyowa Kirin reported positive preliminary Phase 2 data for its antibody. ....

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BIO Digital lands at a time of 'unprecedented industry collaboration'

BIO Digital lands at a time of ‘unprecedented industry collaboration’
By Jenni Spinner
The online pharma event will address the COVID-19 pandemic’s impact on the industry (and vice versa) and innovation in the face of formidable challenges.
While COVID-19’s grip on the globe seems to be gradually waning, organizers of pharma events are still judging on the side of caution and keeping most events virtual for the time being. However, virtual programs such as BIO Digital (scheduled online June 10-11 and June 14-18) still are promising real benefits for attendees.
Theresa Brady, director of communications for events with BIO, spoke with Outsourcing-Pharma about this year’s BIO Digital event, highlights on the agenda, and benefits of taking part in the conference. ....

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Amgen and Kyowa Kirin agree to jointly develop eczema med

Amgen and Kyowa Kirin agree to jointly develop eczema med
1st June 2021
Amgen and Kyowa Kirin have signed an agreement to jointly develop and commercialise KHK4083, a monoclonal antibody (mAb) in development for the treatment of atopic dermatitis – the most common form of eczema.
As part of the agreement, Amgen will take the lead on the development, manufacturing and commercialisation of KHK4083 for all markets globally, excluding Japan where Kyowa Kirin will retain all rights.
Kyowa Kirin will also co-promote the mAb with Amgen in the US and have opt-in rights to co-promote KHK4083 in certain other markets, including Europe and Asia. ....

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Amgen asks FDA for approval of key asthma drug

Dive Brief:
Amgen on Monday said it has submitted for Food and Drug Administration approval its asthma drug hopeful tezepelumab, advancing a medicine that s crucially important to its plans for growing beyond the aging blockbusters that have sustained its business for years.
Tezepelumab, which Amgen has developed with partner AstraZeneca for nearly a decade, is a biologic drug that works to reduce airway inflammation in a new way. By blocking a protein known as TSLP, tezepelumab is thought to prevent the release of other, pro-inflammatory proteins, thereby reducing asthma attacks.
Results from a study called NAVIGATOR, released in November, bore this hypothesis out, showing treatment with the drug reduced attacks in patients with severe asthma. But data from a much smaller clinical trial just one month later raised some questions about how competitive tezepelumab might be. ....

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