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Researcher investigates possible link between obesity and colon cancer


 
Obesity is associated with an increased risk for a broad spectrum of tumors, including colon cancer. And once cancer develops, statistics show that overweight or obese individuals are at higher risk of cancer recurrence and have a decreased chance of survival. The underlying mechanisms for this are unclear.
One of the emerging possibilities with regard to colon cancer is that excess lipids ­ a class of organic compounds, including fats, that are insoluble in water accumulate in both the fat-storing and non-fat-storing tissues of obese individuals. These intracellular lipids are stored in droplets (LDs) and are seen at higher volumes in colonic tumors relative to normal tissues. It is theorized that these droplets not only drive inflammation in the colonic epithelium, but they could also be the energy source that drives colon tumor formation and growth. ....

State Of Louisiana , United States , New Orleans , Suzana Savkovic , Louisiana Cancer Research Center , National Cancer Institute , Biospecimen Laboratory , Tulane Cancer Center , Biospecimen Core Laboratory , Greater New Orleans , Cancer Crusader , Next Generation Sequence Analysis Core , நிலை ஆஃப் லூசியானா , ஒன்றுபட்டது மாநிலங்களில் , புதியது ஆர்லீயந்ஸ் , லூசியானா புற்றுநோய் ஆராய்ச்சி மையம் , தேசிய புற்றுநோய் நிறுவனம் , துலேன் புற்றுநோய் மையம் , அதிகமானது புதியது ஆர்லீயந்ஸ் , புற்றுநோய் சிலுவைப்பான் ,

Study: One in six men with advanced prostate cancer experiences reduced sense of smell and taste


Study: One in six men with advanced prostate cancer experiences reduced sense of smell and taste
One in six men being treated for advanced prostate cancer experiences a reduced sense of smell and taste, a symptom that could cause increased anxiety among patients because it is also a side effect of COVID-19, according to Tulane researchers.
A study published in the journal Supportive Care in Cancer says a reduced sense of smell and taste among some prostate cancer patients is largely associated with poor appetite and weight loss.
Although the data collection for the study predated the COVID-19 pandemic, the results pose important implications for cancer patients undergoing hormone therapy, chemotherapy and/or bone antiresorptive during the coronavirus crisis. ....

United States , New Orleans , Lydia Chow , Elisa Ledet , Oliver Sartor , Emily Henderson , Patrick Cotogno , Sarah Alonzi , Emma Ernst , Laura Perry , Michael Hoerger , Charlotte Manogue , Tulane School Of Science , Louisiana Cancer Research Center , Tufts University School Of Medicine , Tulane Cancer Center , Translational Science Center , Tulane Department Of Psychology , Supportive Care , Tulane Department , Louisiana Clinical , Louisiana Cancer Research , Tulane School , Tulane Cancer , Internal Medicine , Keck School ,