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Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes


Metformin drug decreases mortality rate in COVID-19 patients with type 2 diabetes
Use of the diabetes drug metformin before a diagnosis of COVID-19 is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19.
This beneficial effect remained, even after correcting for age, sex, race, obesity, and hypertension or chronic kidney disease and heart failure.
Anath Shalev, M.D, Study Lead Author and Director of Comprehensive Diabetes Center, University of Alabama at Birmingham
Since similar results have now been obtained in different populations from around the world including China, France and a UnitedHealthcare analysis this suggests that the observed reduction in mortality risk associated with metformin use in subjects with Type 2 diabetes and COVID-19 might be generalizable, Shalev said. ....

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Metformin use reduces risk of death for patients with COVID-19 and diabetes


Credit: UAB
BIRMINGHAM, Ala. - Use of the diabetes drug metformin before a diagnosis of COVID-19 is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19.
This beneficial effect remained, even after correcting for age, sex, race, obesity, and hypertension or chronic kidney disease and heart failure, said Anath Shalev, M.D., director of UAB s Comprehensive Diabetes Center and leader of the study.
Since similar results have now been obtained in different populations from around the world including China, France and a UnitedHealthcare analysis this suggests that the observed reduction in mortality risk associated with metformin use in subjects with Type 2 diabetes and COVID-19 might be generalizable, Shalev said. ....

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