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Global Dental Partnering Deals Report & Directory 2010-2021: Contract Documents for Over 250 Dental Deals

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ResearchAndMarkets.com s offering.
The Global Dental Partnering 2010-2021 report provides comprehensive access to available deals and contract documents for over 250 dental deals.
Most of the deals included within the report occur when a licensee obtains a right or an option right to license a licensor s product or technology. More often these days these deals tend to be multi-component including both a collaborative R&D and a commercialization of outcomes element.
The report takes readers through the comprehensive Dental disease deal trends, key players and top deal values allowing the understanding of how, why and under what terms companies are currently entering Dental deals. ....

United States , New South Wales , City Of , United Kingdom , Pierre Fabre , Solasia Pharma , Arcoral Pharma , Moberg Pharma , Implante Nacional , Mars Petcare , Advanz Pharma , Exzell Pharma , Zimmer Biomet , Henry Schein , Laura Wood , Denmat Holdings , University Of Cologne , Terso Solutions , University Of Lyon , Department Of Defense , Jazz Pharmaceuticals , American Academy Of Implant Dentistry Foundation , Dechra Pharmaceuticals , Forsyth Institute , Us Army , University Of Illinois At Chicago ,

SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models

Science for just $15 USD.
Short circuiting solid tumors
Two major hurdles in chimeric antigen receptor (CAR) T cell therapy for solid tumors are ensuring specificity to tumor cells without affecting healthy cells and avoiding tumor escape due to antigen loss. To address these challenges, Hyrenius-Wittsten
et al. and Choe
et al. developed synthetic Notch (synNotch)–CAR T cells targeting solid tumor antigens and used them to treat mouse models of mesothelioma, ovarian cancer, and glioblastoma. In both studies, the authors demonstrated that synNotch-CAR T cells were better at controlling tumors than traditional CAR T cells and did not result in toxicity or damage to healthy tissue. These results suggest that synNotch-CAR T cells may be an effective treatment strategy for solid tumors. ....

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