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Effect Of Stopping RAS Inhibitors In Patients With Chronic Kidney Disease


Effect Of Stopping RAS Inhibitors In Patients With Chronic Kidney Disease
by Pooja Shete on 
January 1, 2021 at 8:08 PM
Certain small studies suggest that a group of medications called RAS inhibitors which are used for the treatment of hypertension, may be harmful in patients with advanced chronic kidney disease. Therefore physicians often stop the treatment with these drugs in such patients.
Research conducted at Karolinska Institutet shows that although stopping RAS inhibitors is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events, and death.
The research conducted at Karolinska Institutet is published in the ....

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Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease


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IMAGE: Principal investigator Juan Jesus Carrero, professor at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet in Sweden.
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Credit: Ulf Sirborn.
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in
The Journal of the American Society of Nephrology. ....

United States , United Kingdom , The Netherlands , Edouardl Fu , Marie Evans , Karolinska Institutet , Catherinem Clase , Lauriea Tomlinson , Van Diepen , Juanj Carrero , Edouard Fu , Juan Jesus Carrero , Friedow Dekker , Mcmaster University Canada , Department Of Clinical Epidemiology , Westman Foundation , Department Of Medical Epidemiology , Lung Foundation , Swedish Research Council , Journal Of The American Society Nephrology , Leiden University Medical Center , London School Of Hygiene , Leiden University Medical Center The Netherlands , American Society , Phd Candidate , Clinical Epidemiology ,

Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease


Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in
The Journal of the American Society of Nephrology.
Chronic kidney disease (CKD) affects approximately ten percent of the global population. Hypertension is the most common comorbidity. Patients with CKD have an increased risk of cardiovascular disease and death. ....

United States , United Kingdom , The Netherlands , Karolinska Institutet , Juan Jesus Carrero , Edouard Fu , Emily Henderson , Mcmaster University Canada , Department Of Clinical Epidemiology , Westman Foundation , Department Of Medical Epidemiology , Lung Foundation , Swedish Research Council , Journal Of The American Society Nephrology , Leiden University Medical Center , London School Of Hygiene , Leiden University Medical Center The Netherlands , American Society , Phd Candidate , Clinical Epidemiology , Swedish Quality Registers , Swedish Renal Registry , Jesus Carrero , Principal Investigator , Medical Epidemiology , Mcmaster University ,

Stopping RAS inhibitors tied to worse outcomes in patients with advanced chronic kidney disease